Varaico: Literature-Extracted Genetic Variants

Gene:MTHFR
Variant:p.I226T
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MTHFR

NM_005957.5:p.I226T

Associated Papers

Congenital heart disease and folate pathway gene polymorphisms: findings from a North Indian cohort.

Kukshal P et al.

Bmc Cardiovascular Disorders, 2026

Association of epistatic effects of MTHFR, ACE, APOB, and APOE gene polymorphisms with the risk of myocardial infarction and unstable angina in Egyptian patients.

Taha M et al.

Gene, 2024

The Genetic Basis of Strokes in Pediatric Populations and Insight into New Therapeutic Options.

Jankovic M et al.

International Journal of Molecular Sciences, 2022

Methylenetetrahydrofolate Reductase (MTHFR) C677T and A1298C Polymorphisms in Georgian Females with Hypothyroidism.

Kvaratskhelia T et al.

Global Medical Genetics, 2020

Clinical utility of ABCB1 genotyping for preventing toxicity in treatment with irinotecan.

Salvador-Martín S et al.

Pharmacological Research, 2018

Maternal genetic polymorphisms and unexplained recurrent miscarriage: a systematic review and meta-analysis.

Shi X et al.

Clinical Genetics, 2017

Genetic variations of MTHFR gene and their association with preterm birth in Korean women.

Hwang IW et al.

Medicina (kaunas, Lithuania), 2017

Molecular and biochemical investigations of patients with intermediate or severe hyperhomocysteinemia.

Sørensen JT et al.

Molecular Genetics and Metabolism, 2016

Association between methylenetetrahydrofolate reductase (MTHFR) polymorphism and carotid intima medial thickness progression in post ischaemic stroke patient.

Pramukarso DT et al.

Annals of Translational Medicine, 2015

Clinical Relevance of MTHFR, eNOS, ACE, and ApoE Gene Polymorphisms and Serum Vitamin Profile among Malay Patients with Ischemic Stroke.

Wei LK et al.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, 2015

Association between the MTHFR C677T polymorphism and gastric cancer susceptibility: A meta-analysis of 5,757 cases and 8,501 controls.

Chen L et al.

Oncology Letters, 2015

Association of MTHFR genetic variants C677T and A1298C on predisposition to spontaneous abortion in Slavonic population.

Hubacek JA et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2015

Association between Interleukin-8-251A/T polymorphism and gastric cancer susceptibility: a meta-analysis based on 5286 cases and 8000 controls.

Zhang Y et al.

International Journal of Clinical and Experimental Medicine, 2015

Genetic, epigenetic, and environmental contributions to neural tube closure.

Wilde JJ et al.

Annual Review of Genetics, 2014

Clinical significance of determining plasma homocysteine: case-control study on arterial and venous thrombotic patients.

Vuckovic BA et al.

Croatian Medical Journal, 2013

Genomic studies of GVHD-lessons learned thus far.

Ting C et al.

Bone Marrow Transplantation, 2013

Evaluation of the MTHFR A1298C variant in leukoaraiosis.

Szolnoki Z et al.

Journal of Molecular Neuroscience : Mn, 2012

Placental markers of folate-related metabolism in preeclampsia.

Mislanova C et al.

Reproduction (cambridge, England), 2011

Role of methylenetetrahydrofolate reductase gene (MTHFR) 677C>T polymorphism in pediatric cerebrovascular disorders.

Alsayouf H et al.

Journal of Child Neurology, 2011

Characterisation of a human liver cystathionine beta synthase mRNA sequence corresponding to the c.[833T>C;844_845ins68] mutation in CBS gene.

Chassé JF et al.

Molecular and Cellular Biochemistry, 2009

Immunoregulatory gene polymorphisms and graft-versus-host disease.

Conway SE et al.

Expert Review of Clinical Immunology, 2009

Analysis of polymorphism in renin angiotensin system and other related genes in South Indian chronic kidney disease patients.

Anbazhagan K et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2009

Genetic and environmental influences on plasma homocysteine: results from a Danish twin study.

Bathum L et al.

Clinical Chemistry, 2007

Methylenetetrahydrofolate reductase C677T polymorphism in adult patients with lymphoproliferative disorders and its effect on chemotherapy.

Timuragaoglu A et al.

Annals of Hematology, 2006

Effect of polymorphisms of the MTHFR and APOE genes on susceptibility to diabetes and severity of diabetic retinopathy in Brazilian patients.

Errera FI et al.

Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologica, 2006

Polymorphisms in the MTHFR gene and their possible association with susceptibility to childhood acute lymphocytic leukemia in an Indian population.

Reddy H et al.

Leukemia & Lymphoma, 2006

Association of 677C>T polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene with bipolar disorder and schizophrenia.

Kempisty B et al.

Neuroscience Letters, 2006

The MTHFR CT polymorphism confers a high risk for stroke in both homozygous and heterozygous T allele carriers with Type 2 diabetes.

Hermans MP et al.

Diabetic Medicine : a Journal of the British Diabetic Association, 2006

Molecular analysis of homocystinuria in Brazilian patients.

Porto MP et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2005

Genetic variation in the MTHFR gene influences thiopurine methyltransferase activity.

Arenas M et al.

Clinical Chemistry, 2005

Genetic approaches in the study of risk factors for cervical artery dissection.

Grond-Ginsbach G et al.

Frontiers of Neurology and Neuroscience, 2005

Methylenetetrahydrofolate reductase (MTHFR) gene 677C>T and 1298A>C polymorphisms are associated with differential apoptosis of leukemic B cells in vitro and disease progression in chronic lymphocytic leukemia.

Nückel H et al.

Leukemia, 2004

Is hyperhomocysteinemia related to widowers' stroke syndrome?

Kobayashi S

Internal Medicine (tokyo, Japan), 2004

Methylenetetrahydrofolate reductase gene polymorphisms in black South Africans and the association with preeclampsia.

Pegoraro RJ et al.

Acta Obstetricia Et Gynecologica Scandinavica, 2004

Genetics of intima-media thickness.

Zannad F et al.

Current Opinion in Lipidology, 2003

The Siblings With Ischemic Stroke Study (SWISS) protocol.

Meschia JF et al.

Bmc Medical Genetics, 2002

Clinical relevance of genetic risk factors for thrombosis in paediatric oncology patients with central venous catheters.

Wermes C et al.

European Journal of Pediatrics, 1999

Evaluation of genetic risk factors for silent brain infarction.

Notsu Y et al.

Stroke, 1999

Plasma homocyst(e)ine concentration, but not MTHFR genotype, is associated with variation in carotid plaque area.

Spence JD et al.

Stroke, 1999

ACE, MTHFR, factor V Leiden, and APOE polymorphisms in patients with vascular and Alzheimer's dementia.

Chapman J et al.

Stroke, 1998

[Apo(a) phenotype as a risk factor for the silent brain infarction].

Notsu Y et al.

Rinsho Byori. the Japanese Journal of Clinical Pathology, 1997

Variants in the dihydropyrimidine dehydrogenase, methylenetetrahydrofolate reductase and thymidylate synthase genes predict early toxicity of 5-fluorouracil in colorectal cancer patients.

Kristensen MH et al.

The Journal of International Medical Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."