Associated Papers
Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth.
Sawade L et al.
Nature Communications, 2020
Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons.
Narayanan P et al.
Elife, 2018
Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies.
Vaccari I et al.
Plos Genetics, 2011
Endosomal targeting of the phosphoinositide 3-phosphatase MTMR2 is regulated by an N-terminal phosphorylation site.
Franklin NE et al.
The Journal of Biological Chemistry, 2011
The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate AKT signalling.
Berger P et al.
Journal of Cellular and Molecular Medicine, 2011
The phosphoinositide 3-phosphatase MTMR2 interacts with PSD-95 and maintains excitatory synapses by modulating endosomal traffic.
Lee HW et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2010
Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2.
Berger P et al.
Human Molecular Genetics, 2006
Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome.
Begley MJ et al.
Molecular Cell, 2003
Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1.
Berger P et al.
Human Molecular Genetics, 2002
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