Varaico: Literature-Extracted Genetic Variants

Gene:MTNR1B
Variant:p.L60R
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MTNR1B

NM_005959.5:p.L60R

Associated Papers

Rare MTNR1B variants causing diminished MT2 signalling associate with elevated HbA1c levels but not with type 2 diabetes.

Sørensen KV et al.

Diabetologia, 2025

Association of rs3027178 polymorphism in the circadian clock gene PER1 with susceptibility to Alzheimer's disease and longevity in an Italian population.

Bacalini MG et al.

Geroscience, 2022

34921659 (PubMed )
Supplement: 11357_2021_477_MOESM3_ESM.xlsx › rare_variants_AD

Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants.

Plouffe B et al.

Acs Pharmacology & Translational Science, 2022

Minireview: Toward the establishment of a link between melatonin and glucose homeostasis: association of melatonin MT2 receptor variants with type 2 diabetes.

Karamitri A et al.

Molecular Endocrinology (baltimore, Md.), 2013

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes.

Bonnefond A et al.

Nature Genetics, 2012

MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans.

Andersson EA et al.

Diabetes, 2010

[Involvement of melatonin MT2 receptor mutants in type 2 diabetes development].

Karamitri A et al.

Medecine Sciences : M/s, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."