Varaico: Literature-Extracted Genetic Variants

Gene:MTOR
Variant:p.A2420V
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MTOR

NM_004958.4:p.A2420V

Associated Papers

mTOR Variants Activation Discovers PI3K-like Cryptic Pocket, Expanding Allosteric, Mutant-Selective Inhibitor Designs.

Liu Y et al.

Journal of Chemical Information and Modeling, 2025

39792006 (PubMed )
Supplement: ci4c02022_si_002.xlsx › Sheet1

Evaluation of an institutional series of low-grade oncocytic tumor (LOT) of the kidney and review of the mutational landscape of LOT.

Ricci C et al.

Virchows Archiv : an International Journal of Pathology, 2023

Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures.

Alcaniz J et al.

Frontiers in Oncology, 2023

37114125 (PubMed )
Supplement: Table_1.xlsx › Mutations

Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients.

Koyama T et al.

Bmc Cancer, 2019

30709382 (PubMed )
Supplement: 12885_2019_5313_MOESM2_ESM.xlsx › supplementary_2_filtered

Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor.

Rodrik-Outmezguine VS et al.

Nature, 2016

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