Varaico: Literature-Extracted Genetic Variants

Gene:MTOR
Variant:p.Y1463S
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MTOR

NM_004958.4:p.Y1463S

Associated Papers

Integrative omics analyses broaden treatment targets in human cancer.

Sengupta S et al.

Genome Medicine, 2018

30053901 (PubMed )
Supplement: 13073_2018_564_MOESM2_ESM.xlsx › 13

3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets.

Gao J et al.

Genome Medicine, 2017

Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin.

Xu J et al.

The Journal of Clinical Investigation, 2016

Cross-cancer profiling of molecular alterations within the human autophagy interaction network.

Lebovitz CB et al.

Autophagy, 2015

26208877 (PubMed )
Supplement: kaup-11-09-1067362-s001.zip › 1067362_supplemental_files › 2014AUTO0485R1-s03.xlsx › KIRC-mutations

A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity.

Grabiner BC et al.

Cancer Discovery, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."