Associated Papers
Exploration of Homocysteine Metabolism and Genetics in Autism Spectrum Disorder.
Rouphael M et al.
Nutrients, 2025
Methylomic Changes in MTHFR Promoter Region, along with the Heterozygous C677T Polymorphism, Contribute to the Risk of Thrombotic Stroke.
Zain AM et al.
Journal of Molecular Neuroscience : Mn, 2025
Can Global DNA Methylation Be Influenced by Polymorphisms in Genes Involved in Epigenetic Mechanisms? A Review.
de Oliveira NFP et al.
Genes, 2024
Association of c.+677 C>T (rs1801133) and c.+1298 A>C (rs1801131) MTHFR genetic variants with cardiometabolic and disease risk in systemic lupus erythematosus patients: A cross-sectional study.
Pesqueda-Cendejas K et al.
Lupus, 2024
A narrative review on the role of folate-mediated one-carbon metabolism and its associated gene polymorphisms in posing risk to preeclampsia.
Mahmood S et al.
Clinical and Experimental Hypertension (new York, N.y. : 1993), 2021
Association Analysis of Methylenetetrahydrofolate Reductase Common Gene Polymorphisms with Breast Cancer Risk in an Iranian Population: A Case-Control Study and a Stratified Analysis.
Karimian M et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2020
Pharmacogenomics, biomarker network, and allele frequencies in colorectal cancer.
López-Cortés A et al.
The Pharmacogenomics Journal, 2020
Genetic Variants of Homocysteine Metabolism, Homocysteine, and Frailty - Rugao Longevity and Ageing Study.
Ma T et al.
The Journal of Nutrition, Health & Aging, 2020
Predicting the functional and structural consequences of nsSNPs in human methionine synthase gene using computational tools.
Desai M et al.
Systems Biology in Reproductive Medicine, 2019
Genetic polymorphisms in folate metabolism as risk for Down syndrome in the southern China.
Jiajin L et al.
The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2019
Interaction between alcohol consumption and methylenetetrahydrofolate reductase polymorphisms in thyroid cancer risk: National Cancer Center cohort in Korea.
Yang S et al.
Scientific Reports, 2018
Effect of B9 and B12 vitamin intake on semen parameters and fertility of men with MTHFR polymorphisms.
Najafipour R et al.
Andrology, 2017
Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms in oral squamous cell carcinoma in south-east Iran.
Miri-Moghaddam E et al.
Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2016
Breast cancer risk associated with gene expression and genotype polymorphisms of the folate-metabolizing MTHFR gene: a case-control study in a high altitude Ecuadorian mestizo population.
López-Cortés A et al.
Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2015
Variants in MTHFR gene and neural tube defects susceptibility in China.
Wang Y et al.
Metabolic Brain Disease, 2015
Methylation diet and methyl group genetics in risk for adenomatous polyp occurrence.
Lucock M et al.
Bba Clinical, 2015
Effect of genetic polymorphisms involved in folate metabolism on the concentration of serum folate and plasma total homocysteine (p-tHcy) in healthy subjects after short-term folic acid supplementation: a randomized, double blind, crossover study.
Cabo R et al.
Genes & Nutrition, 2015
MTHFR C677T gene polymorphism and head and neck cancer risk: a meta-analysis based on 23 publications.
Niu YM et al.
Disease Markers, 2015
Elevated homocysteine level and folate deficiency associated with increased overall risk of carcinogenesis: meta-analysis of 83 case-control studies involving 35,758 individuals.
Zhang D et al.
Plos One, 2015
Effects of MTHFR genetic polymorphisms on toxicity and clinical response of irinotecan-based chemotherapy in patients with colorectal cancer.
Li P et al.
Genetic Testing and Molecular Biomarkers, 2014
Pharmacogenetic considerations for acute lymphoblastic leukemia therapies.
Dulucq S et al.
Expert Opinion on Drug Metabolism & Toxicology, 2014
5,10-Methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTRR), and methionine synthase reductase (MTR) gene polymorphisms and adult meningioma risk.
Zhang J et al.
Journal of Neuro-oncology, 2013
Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with aura.
Roecklein KA et al.
Cephalalgia : an International Journal of Headache, 2013
A candidate gene study of one-carbon metabolism pathway genes and colorectal cancer risk.
Martinelli M et al.
The British Journal of Nutrition, 2013
Association of polymorphisms in DNMT1, DNMT3A, DNMT3B, MTHFR and MTRR genes with global DNA methylation levels and prognosis of autoimmune thyroid disease.
Arakawa Y et al.
Clinical and Experimental Immunology, 2012
Evaluation of plasma homocysteine level according to the C677T and A1298C polymorphism of the enzyme MTHRF in type 2 diabetic adults.
Mello AL et al.
Arquivos Brasileiros De Endocrinologia E Metabologia, 2012
Folate metabolism-related gene polymorphisms and susceptibility to primary liver cancer in North China.
Cui LH et al.
Medical Oncology (northwood, London, England), 2012
Oxidative stress-related biomarkers in autism: systematic review and meta-analyses.
Frustaci A et al.
Free Radical Biology & Medicine, 2012
Genetic polymorphisms of genes involved in DNA repair and metabolism influence micronucleus frequencies in human peripheral blood lymphocytes.
Dhillon VS et al.
Mutagenesis, 2011
Genetics, cytogenetics, and epigenetics of colorectal cancer.
Migliore L et al.
Journal of Biomedicine & Biotechnology, 2011
Molecular characterization of five patients with homocystinuria due to severe methylenetetrahydrofolate reductase deficiency.
Urreizti R et al.
Clinical Genetics, 2010
MTR polymorphic variant A2756G and retinoblastoma risk in Brazilian children.
de Lima EL et al.
Pediatric Blood & Cancer, 2010
Methylenetetrahydrofolate reductase gene polymorphism in diabetes and obesity.
Tavakkoly Bazzaz J et al.
Molecular Biology Reports, 2010
Investigation of inter-individual variability of the one-carbon folate pathway: a bioinformatic and genetic review.
Carr DF et al.
The Pharmacogenomics Journal, 2009
Non-apolipoprotein E and apolipoprotein E genetics of sporadic Alzheimer's disease.
Seripa D et al.
Ageing Research Reviews, 2009
The effect of 677C>T and 1298A>C MTHFR polymorphisms on sulfasalazine treatment outcome in rheumatoid arthritis.
Pawlik A et al.
Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologica, 2009
Homocysteine level and metabolism in ischemic stroke in the population of Northern Poland.
Sawuła W et al.
Clinical Biochemistry, 2009
A network approach to micronutrient genetics: interactions with lipid metabolism.
Lietz G et al.
Current Opinion in Lipidology, 2009
Effect of the methylenetetrahydrofolate reductase gene polymorphisms on homocysteine, folate and vitamin B12 in patients with bipolar disorder and relatives.
Ozbek Z et al.
Progress in Neuro-psychopharmacology & Biological Psychiatry, 2008
Polymorphisms of methionine metabolism and susceptibility to meningioma formation: laboratory investigation.
Semmler A et al.
Journal of Neurosurgery, 2008
Polymorphisms of methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), methionine synthase reductase (MTRR), and thymidylate synthase (TYMS) in multiple myeloma risk.
Lima CS et al.
Leukemia Research, 2008
Screening for methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Indian patients with idiopathic mental retardation.
Dutta S et al.
Nutritional Neuroscience, 2008
Hyperhomocysteinemia and thrombosis: an overview.
Eldibany MM et al.
Archives of Pathology & Laboratory Medicine, 2007
Polymorphisms in the MTHFR and VDR genes and skin cancer risk.
Han J et al.
Carcinogenesis, 2007
Polymorphism C776G in the transcobalamin II gene and homocysteine, folate and vitamin B12 concentrations. Association with MTHFR C677T and A1298C and MTRR A66G polymorphisms in healthy children.
Aléssio AC et al.
Thrombosis Research, 2007
[Genetic determinants of childhood leukemia].
Sinnett D et al.
Bulletin Du Cancer, 2006
[Frequencies of C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene at the early stage of human individual development].
Nazarenko MS et al.
Genetika, 2006
[Study on the relations between genetic polymorphisms in methylenetetrahydrofolate reductase, methionine synthase and the risk of pancreatic cancer].
Wang L et al.
Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, 2006
Challenges identifying genetic determinants of pediatric cancers--the childhood leukemia experience.
Sinnett D et al.
Familial Cancer, 2006
Association of MTRRA66G polymorphism (but not of MTHFR C677T and A1298C, MTRA2756G, TCN C776G) with homocysteine and coronary artery disease in the French population.
Guéant-Rodriguez RM et al.
Thrombosis and Haemostasis, 2005