Varaico: Literature-Extracted Genetic Variants

Gene:MTR
Variant:p.D919G
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MTR

NM_000254.3:p.D919G

Associated Papers

Congenital heart disease and folate pathway gene polymorphisms: findings from a North Indian cohort.

Kukshal P et al.

Bmc Cardiovascular Disorders, 2026

Distribution of Thrombophilia-Related Genetic Polymorphisms in Women with Reproductive Disorders.

Kurmanova A et al.

Biomedicines, 2026

Evaluating the Impact of Folate on Male Infertility Using Mendelian Randomization: A Comprehensive Analysis.

Wang W et al.

The World Journal of Men's Health, 2026

Relationship between MTHFR, MTRR gene polymorphisms and H-type hypertension: a systematic review and meta-analysis.

Gao L et al.

Annals of Human Biology, 2025

Common Methylenetetrahydrofolate Reductase Polymorphism MTHFR 677C>T (rs1801133), Plasma Homocysteine, and Non-Valvular Atrial Fibrillation in Overweight/Obese Patients: Causality Indicated by Mediation and One-Sample Mendelian Randomization Analysis.

Levicki R et al.

Diagnostics (basel, Switzerland), 2025

41300894 (PubMed )
Supplement: diagnostics-15-02870-s001.zip › diagnostics-3921087-supplementary.pdf

Methylenetetrahydrofolate reductase (MTHFR) 677C>T rs1801133 genetic variant, homocysteine, folate, and vitamin B12 levels in patients with multiple sclerosis: a scoping review.

Ribeiro CM et al.

Multiple Sclerosis and Related Disorders, 2025

Methylenetetrahydrofolate Reductase and Methionine Synthase Reductase Polymorphisms: Genetic Predictors of Congenital Heart Disease Subtypes.

Tripathi S et al.

Cureus, 2025

Genetic susceptibility to retinoblastoma: A meta-analysis of single-nucleotide polymorphisms across global populations.

Gupta S et al.

Journal of Cancer Research and Therapeutics, 2025

Genotype Combinations and Genetic Risk Score Analyses of MTHFR, MTRR, and MTR Polymorphisms in Hypothyroidism Susceptibility: A Case-Control Study.

Tabakoglu NT et al.

Current Issues in Molecular Biology, 2025

Association Between MTRR 66 A/G and MTR 2756 A/G Polymorphisms and Response to Methotrexate in Rheumatoid Arthritis. A Meta-analysis.

Lee YH et al.

Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases, 2025

Dietary and Circulating Vitamins, Polymorphisms of Vitamin Metabolism Genes, and the Risk of Gastrointestinal Cancers: A Systematic Review and Meta-Analysis.

Wang XL et al.

Clinical and Translational Gastroenterology, 2025

Synergistic Effects of MTHFR, MTRR, and MTR Gene Variants on Serum Folate Levels and Cognitive Function in Chinese Preschoolers: A Cross-Sectional Study.

Ou L et al.

Nutrients, 2025

To Study the Correlation of Methylenetetrahydrofolate Reductase C677T and MTR (A2756G) Gene Polymorphism in Endometriosis in Women of Reproductive Age Group.

Singh S et al.

Annals of African Medicine, 2025

Safety and Efficacy of High-Dose Folinic Acid in Children with Autism: The Impact of Folate Metabolism Gene Polymorphisms.

Zhang C et al.

Nutrients, 2025

Genomic Exploration of Essential Hypertension in African-Brazilian Quilombo Populations: A Comprehensive Approach with Pedigree Analysis and Family-Based Association Studies.

Magalhães Borges V et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

Methylenetetrahydrofolate Reductase Gene Polymorphism as a Risk Factor for Coronary Artery Disease.

Sowndarya K et al.

Indian Journal of Clinical Biochemistry : Ijcb, 2025

[The role of genetic polymorphisms in folate metabolism genes in the manifestation of migraine in children].

Strozenko LA et al.

Zhurnal Nevrologii I Psikhiatrii Imeni S.s. Korsakova, 2025

Hyperhomocysteinemia in Takayasu arteritis-genetically defined or burden of the proinflammatory state?

Zarur EB et al.

Frontiers in Immunology, 2025

Association of folate metabolism-related enzymes (MTHFR, MYD88, and TP53) and their single nucleotide polymorphisms with breast cancer susceptibility in women from Southwest China: a Bayesian network approach.

Li X et al.

Frontiers in Oncology, 2025

The biological relationship among depression, vitamins B9, B12, and D, and genetic variants: a systematic review.

Soriano-Gonzalez R et al.

Frontiers in Nutrition, 2025

Association between CBS gene T833C, G919A and 844ins68 polymorphisms in the 8th exon region and coronary artery disease: a meta-analysis.

Zhu Z et al.

Clinical and Experimental Hypertension (new York, N.y. : 1993), 2024

Global DNA Methylation Levels Viz-a-Viz Genetic and Biochemical Variations in One Carbon Metabolic Pathway: An Exploratory Study from North India.

Chaudhary V et al.

Biochemical Genetics, 2024

Folate and cobalamin status, indicators, modulators, interactions, and reference ranges from early pregnancy until birth: the Reus-Tarragona birth cohort study.

Santos-Calderón LA et al.

The American Journal of Clinical Nutrition, 2024

MTHFR C677T、MTHFR A1298C、MTRR A66G and MTR A2756G polymorphisms and male infertility risk: a systematic review and meta-analysis.

Li F et al.

Reproductive Biology and Endocrinology : Rb&e, 2024

Do aluminum, boron, arsenic, cadmium, lipoperoxidation, and genetic polymorphism determine male fertility?

Baszyński J et al.

Ecotoxicology and Environmental Safety, 2024

Association of MTR and MTRR polymorphisms with recurrent pregnancy loss: a case control study.

Shaker MM et al.

Molecular Biology Reports, 2024

Polymorphism of Folate Metabolism Genes among Ethnic Kazakh Women with Preeclampsia in Kazakhstan: A Descriptive Study.

Kaldygulova L et al.

Biology, 2024

Homocysteine, blood pressure and gene-diet interactions in relation to vascular function measures of black South Africans.

du Plessis JP et al.

Genes & Nutrition, 2024

Genetic variants of folate metabolism and the risk of multiple sclerosis.

Aşcı AE et al.

Neurological Research, 2024

Effect of Methylfolate, Pyridoxal-5'-Phosphate, and Methylcobalamin (SolowaysTM) Supplementation on Homocysteine and Low-Density Lipoprotein Cholesterol Levels in Patients with Methylenetetrahydrofolate Reductase, Methionine Synthase, and Methionine Synthase Reductase Polymorphisms: A Randomized Controlled Trial.

Pokushalov E et al.

Nutrients, 2024

Single-Nucleotide Polymorphisms Associated with Mercury Levels and Neurological Symptoms: An Overview.

Perini JA et al.

Toxics, 2024

38535959 (PubMed )
Supplement: toxics-12-00226-s001.zip › toxics-2905208-supplementary.pdf

The prevalence and linkage disequilibrium of 21 genetic variations related to thrombophilia, folate cycle, and hypertension in reproductive age women of Rostov region (Russia).

Bordaeva OY et al.

Annals of Human Genetics, 2024

Folate gene polymorphisms CBS 844ins68 and RFC1 A80G and risk of Down syndrome offspring in young Iranian women: A cross-sectional study.

Farajnezhad N et al.

International Journal of Reproductive Biomedicine, 2024

Associations between one-carbon metabolism and valproic acid-induced liver dysfunction in epileptic patients.

Zhu J et al.

Frontiers in Pharmacology, 2024

The Implication of a Polymorphism in the Methylenetetrahydrofolate Reductase Gene in Homocysteine Metabolism and Related Civilisation Diseases.

Zarembska E et al.

International Journal of Molecular Sciences, 2023

Genome-wide interaction analysis of folate for colorectal cancer risk.

Bouras E et al.

The American Journal of Clinical Nutrition, 2023

37640106 (PubMed )
Supplement: mmc2.xlsx › S.11

Common Variants in One-Carbon Metabolism Genes (MTHFR, MTR, MTHFD1) and Depression in Gynecologic Cancers.

Pawlik P et al.

International Journal of Molecular Sciences, 2023

Association of MTR gene polymorphisms with the occurrence of non-syndromic congenital heart disease: a case-control study.

Liu Y et al.

Scientific Reports, 2023

The Role of Genetic Polymorphisms in Differentiated Thyroid Cancer: A 2023 Update.

Tiucă RA et al.

Biomedicines, 2023

Folate in maternal rheumatoid arthritis-filial autism spectrum disorder continuum.

Ravaei A et al.

Reproductive Toxicology (elmsford, N.y.), 2023

[Assessment of the role of nutritional and genetic determinants in the formation of the risk of diseases associated with folate cycle disorders in the population of the Omsk region].

Vilms EA et al.

Voprosy Pitaniia, 2023

Genetic markers for inherited thrombophilia related pregnancy loss and implantation failure in Indian population - implications for diagnosis and clinical management.

Udumudi A et al.

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022

Assessment of MTR Rs1805087 SNP as Possible Modifier of Sickle Cell Disease Severity in a Nigerian Population.

Osunkalu VO et al.

West African Journal of Medicine, 2022

Current perspectives on interethnic variability in multiple myeloma: Single cell technology, population pharmacogenetics and molecular signal transduction.

Gandhi M et al.

Translational Oncology, 2022

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."