Varaico: Literature-Extracted Genetic Variants

Gene:MUS81
Variant:p.D338A
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MUS81

NM_025128.5:p.D338A

Associated Papers

Phosphorylation status of MUS81 is a modifier of Olaparib sensitivity in BRCA2-deficient cells.

Blandino F et al.

Nucleic Acids Research, 2023

ATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop.

Matos DA et al.

Molecular Cell, 2020

MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells.

Lemaçon D et al.

Nature Communications, 2017

MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells.

Lai X et al.

Nature Communications, 2017

Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression.

El Ghamrasni S et al.

Oncogene, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."