Associated Papers
Exploring the basis of heterogeneity of cancer aggressiveness among the mutated POLE variants.
Selves J et al.
Life Science Alliance, 2024
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer.
Wong M et al.
Nature Medicine, 2020
Polymerase proofreading domain mutations: New opportunities for immunotherapy in hypermutated colorectal cancer beyond MMR deficiency.
Bourdais R et al.
Critical Reviews in Oncology/hematology, 2017
Replicative DNA polymerase mutations in cancer.
Heitzer E et al.
Current Opinion in Genetics & Development, 2014
DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis.
Oka S et al.
Cancer Science, 2011
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