Varaico: Literature-Extracted Genetic Variants

Gene:MYH7
Variant:p.K450E
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MYH7

NM_000257.4:p.K450E

Associated Papers

Mavacamten inhibits myosin activity by stabilising the myosin interacting-heads motif and stalling motor force generation.

McMillan SN et al.

Biorxiv : the Preprint Server for Biology, 2025

The mesa trail and the interacting heads motif of myosin II.

Woodhead JL et al.

Archives of Biochemistry and Biophysics, 2020

Comprehensive analysis of the beta-myosin heavy chain gene in 389 unrelated patients with hypertrophic cardiomyopathy.

Van Driest SL et al.

Journal of the American College of Cardiology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."