Associated Papers
Redox Imbalance and Genetic Mutations in Heart Failure: Synergistic Mechanisms and Therapeutic Strategies.
Balakrishnan VK et al.
Genes, 2026
Gene-based Therapies for Genetic Cardiomyopathies: Molecular Medicine for Heart Disease.
Sharma S et al.
The Canadian Journal of Cardiology, 2026
High-Throughput Methods for Variant Functional Assessment in Cardiac Disease.
Dolder RE et al.
Circulation. Genomic and Precision Medicine, 2026
Generation of a PKP2 heterozygous knockout pig model of arrhythmogenic cardiomyopathy.
Li HH et al.
Zoological Research, 2026
Deep-learning analysis of 3D microarchitectural remodeling in hypertrophic cardiomyopathy.
Wei EQ et al.
Science (new York, N.y.), 2026
Setting the stage for cardiomyopathy gene editing trials: a systematic review of isogenic pair use in human induced pluripotent stem cell-derived cardiomyocyte research.
van der Wilt CN et al.
European Heart Journal Open, 2026
Unraveling the cellular characteristics of cardiomyopathy with rare variant-driven gene signatures using multi-omics analysis.
Jeong HE et al.
Scientific Reports, 2025
Tiny genome with big impact: mitochondrial DNA in cardiovascular health.
Yang Y et al.
Journal of Genetics and Genomics = Yi Chuan Xue Bao, 2025
Hypertrophic Cardiomyopathy Phenocopies: Classification, Key Features, and Differential Diagnosis.
Teresi L et al.
Biomedicines, 2025
Precision Medicine in Cardiomyopathy: Advances and Future Directions.
Mehdi M et al.
Clinical Genetics, 2025
Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model.
Steczina S et al.
Journal of Molecular and Cellular Cardiology, 2025
Signaling pathway alterations in hearts of a porcine model harboring a β-myosin heavy chain (MYH7-R403Q) gene variant.
Warren CM et al.
Journal of Molecular and Cellular Cardiology Plus, 2025
Myosin motor dynamics and cardiac function: Insights from in vivo small-angle X-ray scattering and pressure-volume analysis.
Pearson JT et al.
The Journal of Physiology, 2025
Hypertrophic cardiomyopathy management: a systematic review of the clinical practice guidelines and recommendations.
Sanghvi MM et al.
European Heart Journal. Quality of Care & Clinical Outcomes, 2025
Oxford Nanopore Technologies [ONT] Sequencing: Clinical Validation in Genetically Heterogeneous Disorders.
Urtis M et al.
Genes, 2025
Clustered Regularly Interspaced Short Palindromic Repeats Genome Editing for Cardiovascular Disease: The Future Is Here.
Sami N et al.
Cardiology in Review, 2025
Redefining the Genetic Architecture of Hypertrophic Cardiomyopathy: Role of Intermediate-Effect Variants.
García Hernandez S et al.
Circulation, 2025
Tailored therapeutics for cardiomyopathies.
Bakalakos A et al.
Nature Reviews. Cardiology, 2025
A New Era in the Management of Hypertrophic Cardiomyopathy.
Perez-Asensio A et al.
Reviews in Cardiovascular Medicine, 2025
Current and emerging medical and surgical therapy in hypertrophic cardiomyopathy.
Kim KA et al.
Journal of Cardiovascular Imaging, 2025
Cardiac Myosin Inhibitors in Hypertrophic Cardiomyopathy: From Sarcomere to Clinic.
Nakamura K et al.
International Journal of Molecular Sciences, 2025
Yield on Reinterpretation of Genetic Variants in Pediatric Cardiomyopathy.
Suzuki T et al.
Journal of the American Heart Association, 2025
Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model.
Steczina S et al.
Biorxiv : the Preprint Server for Biology, 2025
Hypertrophic Cardiomyopathy: Current Perspectives.
Patel D et al.
Reviews in Cardiovascular Medicine, 2025
Characteristics and pharmacological responsiveness in hiPSC models of inherited cardiomyopathy.
Gerritse M et al.
Pharmacology & Therapeutics, 2025
From Rare Genetic Variants to Polygenic Risk: Understanding the Genetic Basis of Cardiomyopathies.
Garcia-Ruano AB et al.
Journal of Cardiovascular Development and Disease, 2025
Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy.
Wang YJ et al.
Science Translational Medicine, 2025
Heterozygous MYH7 R403Q mutation impairs left atrial mitochondrial function in a Yucatan mini-pig model of genetic nonobstructive hypertrophic cardiomyopathy.
Krause AA et al.
Journal of Applied Physiology (bethesda, Md. : 1985), 2025
Genetic testing and counseling for hypertrophic cardiomyopathy: An evidence-based practice resource of the National Society of Genetic Counselors.
Miller EM et al.
Journal of Genetic Counseling, 2025
Epistasis regulates genetic control of cardiac hypertrophy.
Wang Q et al.
Nature Cardiovascular Research, 2025
A Narrative Review of Current and Investigational Therapies in Hypertrophic Cardiomyopathy.
Ogurek I et al.
Biomedicines, 2025
Investigating the dual role of mitochondrial and nuclear genome variants in pediatric cardiomyopathies.
Temena MA et al.
Scientific Reports, 2025
Probing relaxed myosin states in hypertrophic cardiomyopathy by second harmonic-generation microscopy.
Arecchi G et al.
Biorxiv : the Preprint Server for Biology, 2025
Deciphering epistatic genetic regulation of cardiac hypertrophy.
Wang Q et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
Microvillus inclusion disease-causing MYO5B point mutations exert differential effects on motor function.
Bowman DM et al.
The Journal of Biological Chemistry, 2025
Experimental Models of Hypertrophic Cardiomyopathy: A Systematic Review.
van den Dolder FW et al.
Jacc. Basic to Translational Science, 2025
Hypertrophic Cardiomyopathy Through the Lens of Mitochondria.
Kirichenko TV et al.
Biomedicines, 2025
Advances in the study and treatment of genetic cardiomyopathies.
Parikh VN et al.
Cell, 2025
The Future of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 Gene Therapy in Cardiomyopathies: A Review of Its Therapeutic Potential and Emerging Applications.
Moradi A et al.
Cureus, 2025
Clinical Features and Prospective Outcomes of Thin-Filament Hypertrophic Cardiomyopathy: Intrinsic Data and Comparative Insights from Other Cohorts.
Chumakova OS et al.
Journal of Clinical Medicine, 2025
Pathogenic genes and clinical prognosis in hypertrophic cardiomyopathy.
Hong Y et al.
World Journal of Cardiology, 2025
Mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated TNNI3 c.235C > T variant.
Zhang L et al.
International Journal of Cardiology, 2025
Hypertrophic cardiomyopathy: insights into pathophysiology and novel therapeutic strategies from clinical studies.
Olalekan SO et al.
The Egyptian Heart Journal : (ehj) : Official Bulletin of the Egyptian Society of Cardiology, 2025