Varaico: Literature-Extracted Genetic Variants

Gene:MYH7
Variant:p.A223T
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MYH7

NM_000257.4:p.A223T

Associated Papers

Danicamtiv, a Selective Agonist of Cardiac Myosin, for Dilated Cardiomyopathy: A Phase 2 Open-Label Trial.

Lakdawala NK et al.

Journal of the American College of Cardiology, 2025

Exploring novel MYH7 gene variants using in silico analyses in Korean patients with cardiomyopathy.

Kim OH et al.

Bmc Medical Genomics, 2024

39237976 (PubMed )
Supplement: 12920_2024_2000_MOESM1_ESM.docx

Assessing Cardiac Contractility From Single Molecules to Whole Hearts.

Garg A et al.

Jacc. Basic to Translational Science, 2024

Clinical phenotypic characteristics in patients carrying MYH7-R143Q mutation with hypertrophic cardiomyopathy.

Zhang L et al.

Current Problems in Cardiology, 2024

Genetic Association of Beta-Myosin Heavy-Chain Gene (MYH7) with Cardiac Dysfunction.

Yousaf M et al.

Genes, 2022

Dilated cardiomyopathy myosin mutants have reduced force-generating capacity.

Ujfalusi Z et al.

The Journal of Biological Chemistry, 2018

Controlling load-dependent kinetics of β-cardiac myosin at the single-molecule level.

Liu C et al.

Nature Structural & Molecular Biology, 2018

How do mutations in contractile proteins cause the primary familial cardiomyopathies?

Marston SB

Journal of Cardiovascular Translational Research, 2011

Genetics of dilated cardiomyopathy.

Kärkkäinen S et al.

Annals of Medicine, 2007

Sarcomeric protein mutations in dilated cardiomyopathy.

Chang AN et al.

Heart Failure Reviews, 2005

Novel mutations in sarcomeric protein genes in dilated cardiomyopathy.

Daehmlow S et al.

Biochemical and Biophysical Research Communications, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."