Varaico: Literature-Extracted Genetic Variants

Gene:MYO6
Variant:p.K157R
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MYO6

NM_004999.4:p.K157R

Associated Papers

Motor domain phosphorylation increases nucleotide exchange and turns MYO6 into a faster and stronger motor.

de Jonge JJ et al.

Nature Communications, 2024

Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria.

Kruppa AJ et al.

Developmental Cell, 2018

Myosin VI facilitates connexin 43 gap junction accretion.

Waxse BJ et al.

Journal of Cell Science, 2017

Loss of cargo binding in the human myosin VI deafness mutant (R1166X) leads to increased actin filament binding.

Arden SD et al.

The Biochemical Journal, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."