Varaico: Literature-Extracted Genetic Variants

Gene:NAT1
Variant:p.R286K
Back to variants list

NAT1

NM_000662.8:p.R286K

Associated Papers

Human N-acetyltransferase 2 (NAT2) gene variability in Brazilian populations from different geographical areas.

Lopes MQP et al.

Frontiers in Pharmacology, 2023

Association of NAT-2 gene polymorphisms toward lung cancer susceptibility and prognosis in North Indian patients treated with platinum-based chemotherapy.

Walia HK et al.

Pharmacogenomics, 2022

Association of NAT2 genetic polymorphism with the efficacy of Neurotropin® for the enhancement of aggrecan gene expression in nucleus pulposus cells: a pilot study.

Nakai T et al.

Bmc Medical Genomics, 2021

Genotype-Environment Interaction Analysis of NQO1, CYP2E1, and NAT2 Polymorphisms and the Risk of Childhood Acute Lymphoblastic Leukemia: A Report From the Mexican Interinstitutional Group for the Identification of the Causes of Childhood Leukemia.

Medina-Sanson A et al.

Frontiers in Oncology, 2020

N-acetyl transferase 2/environmental factors and their association as a modulating risk factor for sporadic colon and rectal cancer.

Procopciuc LM et al.

Journal of Clinical Laboratory Analysis, 2017

NAT2 polymorphisms and risk for Parkinson's disease: a systematic review and meta-analysis.

Jiménez-Jiménez FJ et al.

Expert Opinion on Drug Metabolism & Toxicology, 2016

Differential association for N-acetyltransferase 2 genotype and phenotype with bladder cancer risk in Chinese population.

Quan L et al.

Oncotarget, 2016

Expression of NAT2 in immune system cells and the relation of NAT2 gene polymorphisms in the anti-tuberculosis therapy in Mexican mestizo population.

Salazar-González R et al.

Molecular Biology Reports, 2014

Genetic variability in N-acetyltransferase 2 gene determines susceptibility to childhood lymphoid or myeloid leukemia in Brazil.

Zanrosso CW et al.

Leukemia & Lymphoma, 2012

Accuracy of various human NAT2 SNP genotyping panels to infer rapid, intermediate and slow acetylator phenotypes.

Hein DW et al.

Pharmacogenomics, 2012

Polymorphisms in heterocyclic aromatic amines metabolism-related genes are associated with colorectal adenoma risk.

Eichholzer M et al.

International Journal of Molecular Epidemiology and Genetics, 2012

Polymorphism of N-acetyltransferase 2 gene and the susceptibility to alcoholic liver cirrhosis: interaction with smoking.

Yang KC et al.

Alcoholism, Clinical and Experimental Research, 2011

Interethnic diversity of NAT2 polymorphisms in Brazilian admixed populations.

Talbot J et al.

Bmc Genetics, 2010

Sequence analysis of NAT2 gene in Brazilians: identification of undescribed single nucleotide polymorphisms and molecular modeling of the N-acetyltransferase 2 protein structure.

Teixeira RL et al.

Mutation Research, 2010

Comparison of genetic polymorphisms of the NAT2 gene between Korean and four other ethnic groups.

Kang TS et al.

Journal of Clinical Pharmacy and Therapeutics, 2009

N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine.

Hein DW

Expert Opinion on Drug Metabolism & Toxicology, 2009

Genetic polymorphism in N-Acetyltransferase (NAT): Population distribution of NAT1 and NAT2 activity.

Walker K et al.

Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2009

Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.

Sim E et al.

Toxicology, 2008

Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2.

Walraven JM et al.

Current Drug Metabolism, 2008

Genetic susceptibility to atopic dermatitis.

Kiyohara C et al.

Allergology International : Official Journal of the Japanese Society of Allergology, 2008

Worldwide distribution of NAT2 diversity: implications for NAT2 evolutionary history.

Sabbagh A et al.

Bmc Genetics, 2008

Polymorphism of selected enzymes involved in detoxification and biotransformation in relation to lung cancer.

Gresner P et al.

Lung Cancer (amsterdam, Netherlands), 2007

[Detection of mutation in NAT II gene as a method of determination of izoniazyd (INH) acetylation type in human population].

Augustynowicz-Kopeć E et al.

Pneumonologia I Alergologia Polska, 2007

Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens.

Hein DW et al.

International Journal of Cancer, 2006

N-acetyltransferase 2 (NAT2) gene polymorphisms in Parkinson's disease.

Borlak J et al.

Bmc Medical Genetics, 2006

N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk.

Hein DW

Oncogene, 2006

The association of endometriosis risk and genetic polymorphisms involving dioxin detoxification enzymes: a systematic review.

Guo SW

European Journal of Obstetrics, Gynecology, and Reproductive Biology, 2006

Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene.

Machida H et al.

World Journal of Gastroenterology, 2005

NAT2 slow acetylation and GSTM1 null genotypes may increase postmenopausal breast cancer risk in long-term smoking women.

van der Hel OL et al.

Pharmacogenetics, 2003

Genotype and allele frequencies of TPMT, NAT2, GST, SULT1A1 and MDR-1 in the Egyptian population.

Hamdy SI et al.

British Journal of Clinical Pharmacology, 2003

N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis.

Ricart E et al.

The American Journal of Gastroenterology, 2002

Analysis of six SNPs of NAT2 in Ngawbe and Embera Amerindians of Panama and determination of the Embera acetylation phenotype using caffeine.

Jorge-Nebert LF et al.

Pharmacogenetics, 2002

Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility.

Wikman H et al.

Pharmacogenetics, 2001

Genetic susceptibility to childhood acute lymphoblastic leukemia.

Sinnett D et al.

Leukemia & Lymphoma, 2000

N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review.

Brockton N et al.

American Journal of Epidemiology, 2000

Relationship between acetylation polymorphism and risk of atopic diseases.

Gawrońska-Szklarz B et al.

Clinical Pharmacology and Therapeutics, 1999

Identification of a novel allele at the human NAT1 acetyltransferase locus.

Doll MA et al.

Biochemical and Biophysical Research Communications, 1997

[Identification of functionally significant mutations in NAT2 gene using biological microchips].

Kozhekbaeva ZhM et al.

Molekuliarnaia Biologiia, 0

Arylamine N-acetyltransferase 2 Polymorphisms and the Risk of Endometriosis.

Fayez D et al.

Avicenna Journal of Medical Biotechnology, 0

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."