Associated Papers
PharmVar GeneFocus: NAT2-Genetic Variation and Updated Nomenclature.
Papanikolaou G et al.
Clinical Pharmacology and Therapeutics, 2025
Clinical Pharmacogenetics Implementation Consortium Guideline for NAT2 Genotype and Hydralazine Therapy.
Eadon MT et al.
Clinical Pharmacology and Therapeutics, 2025
Pharmacogenomics in Orofacial Clefts Care: Insights from Whole-Genome Sequencing of Case-Parents Trios.
Poku-Adusei E et al.
Journal of Personalized Medicine, 2025
Homozygotes NAT2*5B slow acetylators are highly associated with hepatotoxicity induced by anti-tuberculosis drugs.
El-Jaick KB et al.
Memorias Do Instituto Oswaldo Cruz, 2022
Determination of NAT2 acetylation status in the Greenlandic population.
Geller F et al.
Archives of Toxicology, 2016
Variation in NAT2 acetylation phenotypes is associated with differences in food-producing subsistence modes and ecoregions in Africa.
Podgorná E et al.
Bmc Evolutionary Biology, 2015
Full-gene-sequencing analysis of N-acetyltransferase-2 in an adult Indian population.
Tilak AV et al.
Genetic Testing and Molecular Biomarkers, 2013
Study of NAT2 genetic polymorphism in West African subjects: example of an healthy non-smoker Senegalese population.
Touré A et al.
Molecular Biology Reports, 2012
Arylamine N-acetyltransferase 2 genotypes in a Mexican population.
Taja-Chayeb L et al.
Genetics and Molecular Research : Gmr, 2012
N-Acetyltransferase-2 (NAT2) gene polymorphisms and enzyme activity in Serbs: unprecedented high prevalence of rapid acetylators in a White population.
Djordjevic N et al.
Journal of Clinical Pharmacology, 2011
Sequence analysis of NAT2 gene in Brazilians: identification of undescribed single nucleotide polymorphisms and molecular modeling of the N-acetyltransferase 2 protein structure.
Teixeira RL et al.
Mutation Research, 2010
Comparison of genetic polymorphisms of the NAT2 gene between Korean and four other ethnic groups.
Kang TS et al.
Journal of Clinical Pharmacy and Therapeutics, 2009
N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine.
Hein DW
Expert Opinion on Drug Metabolism & Toxicology, 2009
Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects.
Matimba A et al.
Human Genomics, 2009
Worldwide distribution of NAT2 diversity: implications for NAT2 evolutionary history.
Sabbagh A et al.
Bmc Genetics, 2008
Genetic profile of the arylamine N-acetyltransferase 2 coding gene among individuals from two different regions of Brazil.
Teixeira RL et al.
Mutation Research, 2007
Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene.
Patin E et al.
Human Mutation, 2006