Varaico: Literature-Extracted Genetic Variants

Gene:NAT2
Variant:p.V253V
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NAT2

NM_000015.3:p.V253V

Associated Papers

Distribution and Role of N-acetyltransferase 2 Genetic Polymorphisms in Bladder Cancer Risk in a Lebanese Population

Nasr R et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2017

Arylamine N-acetyltransferase 2 gene polymorphism in an Algerian population.

Chelouti H et al.

Annals of Human Biology, 2017

N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study.

Adole PS et al.

The Indian Journal of Medical Research, 2016

N-Acetyltransferase 2 (NAT2) polymorphism as a risk modifier of susceptibility to pediatric acute lymphoblastic leukemia.

Kamel AM et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2015

NAT2, XRCC1 and hOGG1 polymorphisms, cigarette smoking, alcohol consumption and risk of upper aerodigestive tract cancer.

Marques CR et al.

Anticancer Research, 2014

Full-gene-sequencing analysis of N-acetyltransferase-2 in an adult Indian population.

Tilak AV et al.

Genetic Testing and Molecular Biomarkers, 2013

NAT2 polymorphisms with oral carcinoma susceptibility: a meta-analysis.

Zhuo XL et al.

Molecular Biology Reports, 2012

Arylamine N-acetyltransferase 2 genotypes in a Mexican population.

Taja-Chayeb L et al.

Genetics and Molecular Research : Gmr, 2012

Genetic polymorphism of NAT2 metabolizing enzymes on phenytoin pharmacokinetics in Indian epileptic patients developing toxicity.

Murali M et al.

Cns Neuroscience & Therapeutics, 2012

Accuracy of various human NAT2 SNP genotyping panels to infer rapid, intermediate and slow acetylator phenotypes.

Hein DW et al.

Pharmacogenomics, 2012

Acetylator status and N-acetyltransferase 2 gene polymorphisms; phenotype-genotype correlation with the sulfamethazine test.

Taja-Chayeb L et al.

Pharmacogenetics and Genomics, 2011

Combined effect of CYP1B1 codon 432 polymorphism and N-acetyltransferase 2 slow acetylator phenotypes in relation to breast cancer in the Turkish population.

Ozbek YK et al.

Anticancer Research, 2010

Polymorphisms in NAT2 gene and atherosclerosis in an Algerian population.

Khelil M et al.

Archives of Medical Research, 2010

Sequence analysis of NAT2 gene in Brazilians: identification of undescribed single nucleotide polymorphisms and molecular modeling of the N-acetyltransferase 2 protein structure.

Teixeira RL et al.

Mutation Research, 2010

Comparison of genetic polymorphisms of the NAT2 gene between Korean and four other ethnic groups.

Kang TS et al.

Journal of Clinical Pharmacy and Therapeutics, 2009

N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine.

Hein DW

Expert Opinion on Drug Metabolism & Toxicology, 2009

Genetic polymorphism in N-Acetyltransferase (NAT): Population distribution of NAT1 and NAT2 activity.

Walker K et al.

Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2009

Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes.

Buch SC et al.

Head & Neck, 2008

Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2.

Walraven JM et al.

Current Drug Metabolism, 2008

Genotyping panel for assessing response to cancer chemotherapy.

Dai Z et al.

Bmc Medical Genomics, 2008

18547414 (PubMed )
Supplement: 1755-8794-1-24-S1.xls › SNPs_selected_for_SNPlex_design

Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens.

Hein DW et al.

International Journal of Cancer, 2006

[Comparative analysis of N-acetylation polymorphism in humans as determined by phenotyping and genotyping].

Goldenkova-Pavlova IV et al.

Genetika, 2006

Discordance between N-acetyltransferase 2 phenotype and genotype in a population of Hmong subjects.

Straka RJ et al.

Journal of Clinical Pharmacology, 2006

Arylamine N-acetyltransferase gene polymorphisms: markers for atopic asthma, serum IgE and blood eosinophil counts.

Batra J et al.

Pharmacogenomics, 2006

Simultaneous determination of 7 N-acetyltransferase-2 single-nucleotide variations by allele-specific primer extension assay.

Zhu Y et al.

Clinical Chemistry, 2006

N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk.

Hein DW

Oncogene, 2006

Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene.

Machida H et al.

World Journal of Gastroenterology, 2005

'Comparison of extremes' approach provides evidence against the modifying role of NAT2 polymorphism in lung cancer susceptibility.

Belogubova EV et al.

Cancer Letters, 2005

Lack of association between arylamine N-acetyltransferase 2 (NAT2) polymorphism and systemic sclerosis.

Skretkowicz K et al.

European Journal of Clinical Pharmacology, 2005

TaqMan real time-polymerase chain reaction methods for determination of nucleotide polymorphisms in human N-acetyltransferase-1 (NAT1) and -2 (NAT2).

Hein DW et al.

Current Protocols in Toxicology, 2005

[Restriction analysis of N-acetyltransferase 2 gene in Caucasian population of West Siberia].

Nikishina MV et al.

Genetika, 2004

Functional genomics of C190T single nucleotide polymorphism in human N-acetyltransferase 2.

Zhu Y et al.

Biological Chemistry, 2002

Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms.

Fretland AJ et al.

Pharmacogenetics, 2001

N-Acetyltransferase-2 genetic polymorphism, well-done meat intake, and breast cancer risk among postmenopausal women.

Deitz AC et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2000

N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review.

Brockton N et al.

American Journal of Epidemiology, 2000

Acetylator phenotype and genotype in patients infected with HIV: discordance between methods for phenotype determination and genotype.

O'Neil WM et al.

Pharmacogenetics, 2000

Pitfalls in N-acetyltransferase 2 genotyping.

Cascorbi I et al.

Pharmacogenetics, 1999

A new mutation C759T in the polymorphic N-acetyltransferase (NAT2) gene.

Woolhouse NM et al.

Pharmacogenetics, 1997

N-acetyltransferase (NAT2) polymorphism and breast cancer susceptibility: a lack of association in a case-control study of Turkish population.

Kocabaş NA et al.

International Journal of Toxicology, 0

[The association of NAT2 polymorphisms with sporadic breast cancer].

Artamonov VV et al.

Molekuliarnaia Biologiia, 0

Acetylation genotype and phenotype in patients with systemic lupus erythematosus.

Rychlik-Sych M et al.

Pharmacological Reports : Pr, 0

[Identification of functionally significant mutations in NAT2 gene using biological microchips].

Kozhekbaeva ZhM et al.

Molekuliarnaia Biologiia, 0

Evaluation of Oxidative Stress Response Related Genetic Variants, Pro-oxidants, Antioxidants and Prostate Cancer.

Lavender N et al.

Aims Medical Science, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."