Varaico: Literature-Extracted Genetic Variants

Gene:NAT2
Variant:p.K256E
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NAT2

NM_000015.3:p.K256E

Associated Papers

Genome-wide Gene-by-Sex Interaction Studies Identify Novel Nonsyndromic Orofacial Clefts Risk Locus.

Awotoye W et al.

Journal of Dental Research, 2022

Homozygotes NAT2*5B slow acetylators are highly associated with hepatotoxicity induced by anti-tuberculosis drugs.

El-Jaick KB et al.

Memorias Do Instituto Oswaldo Cruz, 2022

Determination of NAT2 acetylation status in the Greenlandic population.

Geller F et al.

Archives of Toxicology, 2016

Variation in NAT2 acetylation phenotypes is associated with differences in food-producing subsistence modes and ecoregions in Africa.

Podgorná E et al.

Bmc Evolutionary Biology, 2015

26620671 (PubMed )
Supplement: 12862_2015_543_MOESM2_ESM.pdf

Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.

Wang J et al.

Plos One, 2014

25372392 (PubMed )
Supplement: pone.0111694.s006.pdf

Full-gene-sequencing analysis of N-acetyltransferase-2 in an adult Indian population.

Tilak AV et al.

Genetic Testing and Molecular Biomarkers, 2013

Arylamine N-acetyltransferase 2 genotypes in a Mexican population.

Taja-Chayeb L et al.

Genetics and Molecular Research : Gmr, 2012

Sequence analysis of NAT2 gene in Brazilians: identification of undescribed single nucleotide polymorphisms and molecular modeling of the N-acetyltransferase 2 protein structure.

Teixeira RL et al.

Mutation Research, 2010

N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine.

Hein DW

Expert Opinion on Drug Metabolism & Toxicology, 2009

Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects.

Matimba A et al.

Human Genomics, 2009

Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2.

Walraven JM et al.

Current Drug Metabolism, 2008

Sub-Saharan African coding sequence variation and haplotype diversity at the NAT2 gene.

Patin E et al.

Human Mutation, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."