Associated Papers
Pharmacogenetics of First-Line Antitubercular Drugs: An Update.
Manca A et al.
Therapeutic Drug Monitoring, 2026
Pharmacogenomics and mutation informatics: correlation of NAT2 mutations and isoniazid acetylation rate.
Verma S et al.
Drug Discovery Today, 2026
APF2: an improved ensemble method for pharmacogenomic variant effect prediction.
Zhou Y et al.
The Pharmacogenomics Journal, 2024
Direct Comparative Analysis of a Pharmacogenomics Panel with PacBio Hifi® Long-Read and Illumina Short-Read Sequencing.
Barthélémy D et al.
Journal of Personalized Medicine, 2023
Gene Polymorphism of Biotransformation Enzymes and Ciprofloxacin Pharmacokinetics in Pediatric Patients with Cystic Fibrosis.
Zyryanov SK et al.
Biomedicines, 2022
Arylamine N-acetyltransferase acetylation polymorphisms: paradigm for pharmacogenomic-guided therapy- a focused review.
Hein DW et al.
Expert Opinion on Drug Metabolism & Toxicology, 2021
An optimized prediction framework to assess the functional impact of pharmacogenetic variants.
Zhou Y et al.
The Pharmacogenomics Journal, 2019
N-acetyl transferase 2/environmental factors and their association as a modulating risk factor for sporadic colon and rectal cancer.
Procopciuc LM et al.
Journal of Clinical Laboratory Analysis, 2017
Arylamine N-acetyltransferase 2 gene polymorphism in an Algerian population.
Chelouti H et al.
Annals of Human Biology, 2017
Catalytic properties and heat stabilities of novel recombinant human N-acetyltransferase 2 allozymes support existence of genetic heterogeneity within the slow acetylator phenotype.
Hein DW et al.
Archives of Toxicology, 2017
Colorectal Cancer Carcinogenesis: a Multivariate Genetic Model in a Cohort of Romanian Population.
Procopciuc LM et al.
Clinical Laboratory, 2017
N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study.
Adole PS et al.
The Indian Journal of Medical Research, 2016
N-Acetyltransferase 2 (NAT2) polymorphism as a risk modifier of susceptibility to pediatric acute lymphoblastic leukemia.
Kamel AM et al.
Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2015
NAT2, XRCC1 and hOGG1 polymorphisms, cigarette smoking, alcohol consumption and risk of upper aerodigestive tract cancer.
Marques CR et al.
Anticancer Research, 2014
Full-gene-sequencing analysis of N-acetyltransferase-2 in an adult Indian population.
Tilak AV et al.
Genetic Testing and Molecular Biomarkers, 2013
Correlation of N-acetyltransferase 2 genotype with isoniazid acetylation in Polish tuberculosis patients.
Zabost A et al.
Biomed Research International, 2013
Arylamine N-acetyltransferase 2 genotypes in a Mexican population.
Taja-Chayeb L et al.
Genetics and Molecular Research : Gmr, 2012
Genetic polymorphism of NAT2 metabolizing enzymes on phenytoin pharmacokinetics in Indian epileptic patients developing toxicity.
Murali M et al.
Cns Neuroscience & Therapeutics, 2012
Accuracy of various human NAT2 SNP genotyping panels to infer rapid, intermediate and slow acetylator phenotypes.
Hein DW et al.
Pharmacogenomics, 2012
Acetylator status and N-acetyltransferase 2 gene polymorphisms; phenotype-genotype correlation with the sulfamethazine test.
Taja-Chayeb L et al.
Pharmacogenetics and Genomics, 2011
Effects of single nucleotide polymorphisms on human N-acetyltransferase 2 structure and dynamics by molecular dynamics simulation.
Rajasekaran M et al.
Plos One, 2011
Combined effect of CYP1B1 codon 432 polymorphism and N-acetyltransferase 2 slow acetylator phenotypes in relation to breast cancer in the Turkish population.
Ozbek YK et al.
Anticancer Research, 2010
Polymorphisms in NAT2 gene and atherosclerosis in an Algerian population.
Khelil M et al.
Archives of Medical Research, 2010
Sequence analysis of NAT2 gene in Brazilians: identification of undescribed single nucleotide polymorphisms and molecular modeling of the N-acetyltransferase 2 protein structure.
Teixeira RL et al.
Mutation Research, 2010
Comparison of genetic polymorphisms of the NAT2 gene between Korean and four other ethnic groups.
Kang TS et al.
Journal of Clinical Pharmacy and Therapeutics, 2009
N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine.
Hein DW
Expert Opinion on Drug Metabolism & Toxicology, 2009
Study of NAT2 gene polymorphisms in an Indian population: association with plasma isoniazid concentration in a cohort of tuberculosis patients.
Singh N et al.
Molecular Diagnosis & Therapy, 2009
Genetic polymorphism in N-Acetyltransferase (NAT): Population distribution of NAT1 and NAT2 activity.
Walker K et al.
Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2009
Case-control study of oral and oropharyngeal cancer in whites and genetic variation in eight metabolic enzymes.
Buch SC et al.
Head & Neck, 2008
Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2.
Walraven JM et al.
Current Drug Metabolism, 2008
Genotyping panel for assessing response to cancer chemotherapy.
Dai Z et al.
Bmc Medical Genomics, 2008
Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens.
Hein DW et al.
International Journal of Cancer, 2006
[Comparative analysis of N-acetylation polymorphism in humans as determined by phenotyping and genotyping].
Goldenkova-Pavlova IV et al.
Genetika, 2006
Discordance between N-acetyltransferase 2 phenotype and genotype in a population of Hmong subjects.
Straka RJ et al.
Journal of Clinical Pharmacology, 2006
Simultaneous determination of 7 N-acetyltransferase-2 single-nucleotide variations by allele-specific primer extension assay.
Zhu Y et al.
Clinical Chemistry, 2006
N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk.
Hein DW
Oncogene, 2006
Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene.
Machida H et al.
World Journal of Gastroenterology, 2005
'Comparison of extremes' approach provides evidence against the modifying role of NAT2 polymorphism in lung cancer susceptibility.
Belogubova EV et al.
Cancer Letters, 2005
TaqMan real time-polymerase chain reaction methods for determination of nucleotide polymorphisms in human N-acetyltransferase-1 (NAT1) and -2 (NAT2).
Hein DW et al.
Current Protocols in Toxicology, 2005
Functional genomics of C190T single nucleotide polymorphism in human N-acetyltransferase 2.
Zhu Y et al.
Biological Chemistry, 2002
Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms.
Fretland AJ et al.
Pharmacogenetics, 2001
N-Acetyltransferase-2 genetic polymorphism, well-done meat intake, and breast cancer risk among postmenopausal women.
Deitz AC et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2000
Acetylator phenotype and genotype in patients infected with HIV: discordance between methods for phenotype determination and genotype.
O'Neil WM et al.
Pharmacogenetics, 2000
Arylamine N-acetyltransferase (NAT2) genotypes in a Turkish population.
Aynacioglu AS et al.
Pharmacogenetics, 1997
Rodent models of the human acetylation polymorphism: comparisons of recombinant acetyltransferases.
Hein DW et al.
Mutation Research, 1997
Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer.
Cascorbi I et al.
Cancer Research, 1996
N-acetyltransferase (NAT2) polymorphism and breast cancer susceptibility: a lack of association in a case-control study of Turkish population.
Kocabaş NA et al.
International Journal of Toxicology, 0
[The association of NAT2 polymorphisms with sporadic breast cancer].
Artamonov VV et al.
Molekuliarnaia Biologiia, 0
[Identification of functionally significant mutations in NAT2 gene using biological microchips].
Kozhekbaeva ZhM et al.
Molekuliarnaia Biologiia, 0