Associated Papers
Pharmacogenetics of First-Line Antitubercular Drugs: An Update.
Manca A et al.
Therapeutic Drug Monitoring, 2026
Pharmacogenomic heterogeneity of N-acetyltransferase 2: a comprehensive analysis of real world data in Indian tuberculosis patients and from literature and database review.
Thomas L et al.
Annals of Medicine, 2025
Influence of Glutathione S-transferase Mu 1 (GSTM1), Glutathione S-transferase Theta 1 (GSTT1), and N-acetyltransferase 2 (NAT2) Variants on Bladder Cancer Progression and Recurrence Rating: A Bosnian and Herzegovinian Case-Control Study.
Hadziosmanovic O et al.
Cureus, 2025
A study of N-acetyltransferase 2 gene polymorphisms in the Indian population and its relationship with serum isoniazid concentrations in a cohort of tuberculosis patients.
Munshi R et al.
Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace, 2024
Pharmacogenetic variability of tuberculosis biomarkers in native and mestizo Peruvian populations.
Jaramillo-Valverde L et al.
Pharmacology Research & Perspectives, 2024
Influence of N-acetyltransferase 2 polymorphisms and clinical variables on liver function profile of tuberculosis patients.
Thomas L et al.
Expert Review of Clinical Pharmacology, 2024
Towards pharmacogenomics-guided tuberculosis (TB) therapy: N-acetyltransferase-2 genotypes among TB-infected Kenyans of mixed ethnicity.
Njagi LN et al.
Bmc Medical Genomics, 2024
Human N-acetyltransferase 2 (NAT2) gene variability in Brazilian populations from different geographical areas.
Lopes MQP et al.
Frontiers in Pharmacology, 2023
Association of NAT2 genetic polymorphism with the efficacy of Neurotropin® for the enhancement of aggrecan gene expression in nucleus pulposus cells: a pilot study.
Nakai T et al.
Bmc Medical Genomics, 2021
Study on Genotyping Polymorphism and Sequencing of N-Acetyltransferase 2 (NAT2) among Al-Ahsa Population.
Zahra MA et al.
Biomed Research International, 2020
Genotype-Environment Interaction Analysis of NQO1, CYP2E1, and NAT2 Polymorphisms and the Risk of Childhood Acute Lymphoblastic Leukemia: A Report From the Mexican Interinstitutional Group for the Identification of the Causes of Childhood Leukemia.
Medina-Sanson A et al.
Frontiers in Oncology, 2020
Risk of congenital heart diseases associated with NAT2 genetic polymorphisms and maternal polycyclic aromatic hydrocarbons exposure.
Tao J et al.
Prenatal Diagnosis, 2019
NAT2 gene polymorphisms and endometriosis risk: A PRISMA-compliant meta-analysis.
Wei Z et al.
Plos One, 2019
Sequence analysis of the N-acetyltransferase 2 gene (NAT2) among Jordanian volunteers.
Jarrar YB et al.
The Libyan Journal of Medicine, 2018
N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians.
Aklillu E et al.
European Journal of Clinical Pharmacology, 2018
Effect of gene-gene and gene-environment interactions associated with antituberculosis drug-induced hepatotoxicity.
Chamorro JG et al.
Pharmacogenetics and Genomics, 2017
N-acetyl transferase 2/environmental factors and their association as a modulating risk factor for sporadic colon and rectal cancer.
Procopciuc LM et al.
Journal of Clinical Laboratory Analysis, 2017
Arylamine N-acetyltransferase 2 gene polymorphism in an Algerian population.
Chelouti H et al.
Annals of Human Biology, 2017
Catalytic properties and heat stabilities of novel recombinant human N-acetyltransferase 2 allozymes support existence of genetic heterogeneity within the slow acetylator phenotype.
Hein DW et al.
Archives of Toxicology, 2017
Association between NAT2 polymorphisms and the risk of schizophrenia in a Northern Chinese Han population.
Luan Z et al.
Psychiatric Genetics, 2017
N-acetyltransferase 2 polymorphism and breast cancer risk with smoking: a case control study in Japanese women.
Hara A et al.
Breast Cancer (tokyo, Japan), 2017
Factors associated with anti-TB drug-induced hepatotoxicity and genetic polymorphisms in indigenous and non-indigenous populations in Brazil.
Heinrich MM et al.
Tuberculosis (edinburgh, Scotland), 2016
NAT2 gene diversity and its evolutionary trajectory in the Americas.
Bisso-Machado R et al.
The Pharmacogenomics Journal, 2016
NAT2 polymorphisms and risk for Parkinson's disease: a systematic review and meta-analysis.
Jiménez-Jiménez FJ et al.
Expert Opinion on Drug Metabolism & Toxicology, 2016
Genotype and allele frequencies of isoniazid-metabolizing enzymes NAT2 and GSTM1 in Latvian tuberculosis patients.
Igumnova V et al.
Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy, 2016
Differential association for N-acetyltransferase 2 genotype and phenotype with bladder cancer risk in Chinese population.
Quan L et al.
Oncotarget, 2016
Expression of NAT2 in immune system cells and the relation of NAT2 gene polymorphisms in the anti-tuberculosis therapy in Mexican mestizo population.
Salazar-González R et al.
Molecular Biology Reports, 2014
Synergism between the N-acetyltransferase 2 gene and oxidant exposure increases the risk of idiopathic male infertility.
Yarosh SL et al.
Reproductive Biomedicine Online, 2014
Refinement of the prediction of N-acetyltransferase 2 (NAT2) phenotypes with respect to enzyme activity and urinary bladder cancer risk.
Selinski S et al.
Archives of Toxicology, 2013
Full-gene-sequencing analysis of N-acetyltransferase-2 in an adult Indian population.
Tilak AV et al.
Genetic Testing and Molecular Biomarkers, 2013
Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatotoxicity in Tunisian patients with tuberculosis.
Ben Mahmoud L et al.
Pathologie-biologie, 2012
Evaluation of polymorphisms in the sulfonamide detoxification genes NAT2, CYB5A, and CYB5R3 in patients with sulfonamide hypersensitivity.
Sacco JC et al.
Pharmacogenetics and Genomics, 2012
Genetic variability in N-acetyltransferase 2 gene determines susceptibility to childhood lymphoid or myeloid leukemia in Brazil.
Zanrosso CW et al.
Leukemia & Lymphoma, 2012
Accuracy of various human NAT2 SNP genotyping panels to infer rapid, intermediate and slow acetylator phenotypes.
Hein DW et al.
Pharmacogenomics, 2012
Polymorphism of N-acetyltransferase 2 gene and the susceptibility to alcoholic liver cirrhosis: interaction with smoking.
Yang KC et al.
Alcoholism, Clinical and Experimental Research, 2011
Modulation of urinary polycyclic aromatic hydrocarbon metabolites by enzyme polymorphisms in workers of the German Human Bitumen Study.
Rihs HP et al.
Archives of Toxicology, 2011
Association of NAT2 polymorphisms with type 2 diabetes in a population from Bosnia and Herzegovina.
Semiz S et al.
Archives of Medical Research, 2011
Interethnic diversity of NAT2 polymorphisms in Brazilian admixed populations.
Talbot J et al.
Bmc Genetics, 2010
Sequence analysis of NAT2 gene in Brazilians: identification of undescribed single nucleotide polymorphisms and molecular modeling of the N-acetyltransferase 2 protein structure.
Teixeira RL et al.
Mutation Research, 2010
Association of polymorphism in cytochrome P450 2D6 and N-acetyltransferase-2 with Parkinson's disease.
Singh M et al.
Disease Markers, 2010
Comparison of genetic polymorphisms of the NAT2 gene between Korean and four other ethnic groups.
Kang TS et al.
Journal of Clinical Pharmacy and Therapeutics, 2009
Effects of NAT2 polymorphism on SASP pharmacokinetics in Chinese population.
Ma JJ et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 2009
Role of the N-acetyltransferase 2 detoxification system in thyroid cancer susceptibility.
Guilhen AC et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2009
Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2.
Walraven JM et al.
Current Drug Metabolism, 2008
Worldwide distribution of NAT2 diversity: implications for NAT2 evolutionary history.
Sabbagh A et al.
Bmc Genetics, 2008
Arylamine N-acetyltransferases: from structure to function.
Sim E et al.
Drug Metabolism Reviews, 2008
Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer.
Jiao L et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2007
N-acetyltransferase polymorphism among northern Sudanese.
Al-Yahyaee S et al.
Human Biology, 2007
Analysis of associations of NAT2 gene polymorphisms with the risk of lung cancer.
Nikishina MV et al.
Bulletin of Experimental Biology and Medicine, 2007
Association of NAT2 gene substitution mutation T341C with increased risk for head and neck cancer in Tunisia.
Gara S et al.
Acta Oncologica (stockholm, Sweden), 2007