Associated Papers
Structure of human phagocyte NADPH oxidase in the activated state.
Liu X et al.
Nature, 2024
The molecular basis of Rac-GTP action-promoting binding of p67phox to Nox2 by disengaging the β hairpin from downstream residues.
Bechor E et al.
Journal of Leukocyte Biology, 2021
Arachidonic acid induces direct interaction of the p67(phox)-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production.
Matono R et al.
The Journal of Biological Chemistry, 2014
Two CGD Families with a Hypomorphic Mutation in the Activation Domain of p67phox.
Roos D et al.
Journal of Clinical & Cellular Immunology, 2014
A conserved region between the TPR and activation domains of p67phox participates in activation of the phagocyte NADPH oxidase.
Maehara Y et al.
The Journal of Biological Chemistry, 2010
Phosphorylation of serine282 in NADPH oxidase activator 1 by Erk desensitizes EGF-induced ROS generation.
Oh H et al.
Biochemical and Biophysical Research Communications, 2010
Dual role of Rac in the assembly of NADPH oxidase, tethering to the membrane and activation of p67phox: a study based on mutagenesis of p67phox-Rac1 chimeras.
Sarfstein R et al.
The Journal of Biological Chemistry, 2004
Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system.
Price MO et al.
Blood, 2002
Regulation of the neutrophil respiratory burst oxidase. Identification of an activation domain in p67(phox).
Han CH et al.
The Journal of Biological Chemistry, 1998
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