Varaico: Literature-Extracted Genetic Variants

Gene:NCF4
Variant:p.D289A
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NCF4

NM_000631.5:p.D289A

Associated Papers

The domain organization of p67 phox, a protein required for activation of the superoxide-producing NADPH oxidase in phagocytes.

Yuzawa S et al.

Journal of Innate Immunity, 2009

Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production.

Chen J et al.

The Journal of Biological Chemistry, 2007

PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62.

Wilson MI et al.

Molecular Cell, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."