Varaico: Literature-Extracted Genetic Variants

Gene:NCOR2
Variant:p.R243Q
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NCOR2

NM_006312.6:p.R243Q

Associated Papers

Resmetirom Is an Effective Thyromimetics for the Chemical Rescue of Thyroid Hormone Receptor Mutants.

Mitsutani M et al.

Biological & Pharmaceutical Bulletin, 2025

Structural Insights Into Thyroid Hormone Receptors.

Tambones I et al.

Endocrinology, 2024

Analysis of the roles of mutations in thyroid hormone receptor-β by a bacterial biosensor system.

Shi C et al.

Journal of Molecular Endocrinology, 2014

Defective release of corepressor by hinge mutants of the thyroid hormone receptor found in patients with resistance to thyroid hormone.

Safer JD et al.

The Journal of Biological Chemistry, 1998

A role for helix 3 of the TRbeta ligand-binding domain in coactivator recruitment identified by characterization of a third cluster of mutations in resistance to thyroid hormone.

Collingwood TN et al.

The Embo Journal, 1998

Ligand- and nuclear factor-dependent change in hydrophobicity of thyroid hormone beta1 receptor.

Sakurai A et al.

Thyroid : Official Journal of the American Thyroid Association, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."