Varaico: Literature-Extracted Genetic Variants

Gene:NEDD4L
Variant:p.S328A
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NEDD4L

NM_001144967.3:p.S328A

Associated Papers

The phosphorylation site T613 in the β-subunit of rat epithelial Na+ channel (ENaC) modulates channel inhibition by Nedd4-2.

Krueger B et al.

Pflugers Archiv : European Journal of Physiology, 2018

Inducible kidney-specific Sgk1 knockout mice show a salt-losing phenotype.

Faresse N et al.

American Journal of Physiology. Renal Physiology, 2012

Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.

Arroyo JP et al.

Journal of the American Society of Nephrology : Jasn, 2011

14-3-3 isoforms are induced by aldosterone and participate in its regulation of epithelial sodium channels.

Liang X et al.

The Journal of Biological Chemistry, 2006

Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells.

Flores SY et al.

Journal of the American Society of Nephrology : Jasn, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."