Varaico: Literature-Extracted Genetic Variants

Gene:NEIL1
Variant:p.G83D
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NEIL1

NM_024608.4:p.G83D

Associated Papers

The Link Between Human Alkyladenine DNA Glycosylase and Cancer Development.

Kladova OA et al.

International Journal of Molecular Sciences, 2025

Aflatoxin B1-Induced Hepatic Mutagenesis in Mice Expressing Gene-Edited Neil1.

Minko IG et al.

Environmental and Molecular Mutagenesis, 2025

DNA repair and disease: insights from the human DNA glycosylase NEIL family.

Hwang Y et al.

Experimental & Molecular Medicine, 2025

Decoding the Role of NEIL1 Gene in DNA Repair and Lifespan: A Literature Review with Bioinformatics Analysis.

Mohajeri Khorasani A et al.

Advanced Biology, 2024

Functional analyses of single nucleotide polymorphic variants of the DNA glycosylase NEIL1 in sub-Saharan African populations.

Zuckerman JT et al.

Dna Repair, 2023

Genomic analyses of germline and somatic variation in high-grade serous ovarian cancer.

Adamson AW et al.

Journal of Ovarian Research, 2023

37460928 (PubMed )
Supplement: 13048_2023_1234_MOESM2_ESM.xlsx › Table_S10__

Genetic analyses of DNA repair pathway associated genes implicate new candidate cancer predisposing genes in ancestrally defined ovarian cancer cases.

Alenezi WM et al.

Frontiers in Oncology, 2023

Complex Roles of NEIL1 and OGG1: Insights Gained from Murine Knockouts and Human Polymorphic Variants.

Lloyd RS

Dna, 2022

Mouse Embryonic Fibroblasts Isolated From Nthl1 D227Y Knockin Mice Exhibit Defective DNA Repair and Increased Genome Instability.

Marsden CG et al.

Dna Repair, 2022

Mono- and biallelic germline variants of DNA glycosylase genes in colon adenomatous polyposis families from two continents.

Olkinuora AP et al.

Frontiers in Oncology, 2022

Chromatin and other obstacles to base excision repair: potential roles in carcinogenesis.

Caffrey PJ et al.

Mutagenesis, 2020

The double-edged sword of cancer mutations: exploiting neoepitopes for the fight against cancer.

Alvarado-Cruz I et al.

Mutagenesis, 2020

Characterization of rare NEIL1 variants found in East Asian populations.

Minko IG et al.

Dna Repair, 2019

Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer.

Leong TL et al.

Oncogene, 2019

30348992 (PubMed )
Supplement: 41388_2018_536_MOESM6_ESM.xlsx › Germline_Variants

The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation.

Galick HA et al.

Oncotarget, 2017

Single nucleotide polymorphisms in DNA glycosylases: From function to disease.

D'Errico M et al.

Free Radical Biology & Medicine, 2017

NEIL1 p.Gln282Stop variant is predominantly localized in the cytoplasm and exhibits reduced activity in suppressing mutations.

Shinmura K et al.

Gene, 2015

Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: activity, structure, and the effect of editing.

Prakash A et al.

Dna Repair, 2014

NEIL1 responds and binds to psoralen-induced DNA interstrand crosslinks.

McNeill DR et al.

The Journal of Biological Chemistry, 2013

Base excision repair and cancer.

Wallace SS et al.

Cancer Letters, 2012

Oxidatively induced DNA damage: mechanisms, repair and disease.

Dizdaroglu M

Cancer Letters, 2012

Reprint of: gene susceptibility to oxidative damage: from single nucleotide polymorphisms to function.

Simonelli V et al.

Mutation Research, 2012

Gene susceptibility to oxidative damage: from single nucleotide polymorphisms to function.

Simonelli V et al.

Mutation Research, 2012

Variation in base excision repair capacity.

Wilson DM et al.

Mutation Research, 2011

Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma.

Forsbring M et al.

Carcinogenesis, 2009

Human polymorphic variants of the NEIL1 DNA glycosylase.

Roy LM et al.

The Journal of Biological Chemistry, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."