Varaico: Literature-Extracted Genetic Variants

Gene:NEIL1
Variant:p.K242R
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NEIL1

NM_024608.4:p.K242R

Associated Papers

Zα and Zβ Localize ADAR1 to Flipons That Modulate Innate Immunity, Alternative Splicing, and Nonsynonymous RNA Editing.

Herbert A et al.

International Journal of Molecular Sciences, 2025

Functional characterization of single nucleotide polymorphic variants of DNA repair enzyme NEIL1 in South Asian populations.

Zuckerman JT et al.

Dna Repair, 2024

Structural and functional effects of inosine modification in mRNA.

Mendoza HG et al.

Rna (new York, N.y.), 2024

Functional analyses of single nucleotide polymorphic variants of the DNA glycosylase NEIL1 in sub-Saharan African populations.

Zuckerman JT et al.

Dna Repair, 2023

Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification.

Tretter C et al.

Nature Communications, 2023

37532709 (PubMed )
Supplement: 41467_2023_39570_MOESM6_ESM.xlsx › shared_RNA_alt._groups

Meta-Analysis of Keratoconus Transcriptomic Data Revealed Altered RNA Editing Levels Impacting Keratin Genomic Clusters.

Bortoletto E et al.

Investigative Ophthalmology & Visual Science, 2023

The Integrative Studies on the Functional A-to-I RNA Editing Events in Human Cancers.

Wu S et al.

Genomics, Proteomics & Bioinformatics, 2023

Bowhead NEIL1: molecular cloning, characterization, and enzymatic properties.

Holm S et al.

Biochimie, 2023

The A-to-I editing of KPC1 promotes intrahepatic cholangiocarcinoma by attenuating proteasomal processing of NF-κB1 p105 to p50.

Gao C et al.

Journal of Experimental & Clinical Cancer Research : Cr, 2022

36476255 (PubMed )
Supplement: 13046_2022_2549_MOESM1_ESM.doc

ADAR1 and its implications in cancer development and treatment.

Baker AR et al.

Trends in Genetics : Tig, 2022

p53-NEIL1 co-abnormalities induce genomic instability and promote synthetic lethality with Chk1 inhibition in multiple myeloma having concomitant 17p13(del) and 1q21(gain).

Teoh PJ et al.

Oncogene, 2022

Genetic variation and microRNA targeting of A-to-I RNA editing fine tune human tissue transcriptomes.

Park E et al.

Genome Biology, 2021

The majority of A-to-I RNA editing is not required for mammalian homeostasis.

Chalk AM et al.

Genome Biology, 2019

Characterization of rare NEIL1 variants found in East Asian populations.

Minko IG et al.

Dna Repair, 2019

Widespread RNA editing dysregulation in brains from autistic individuals.

Tran SS et al.

Nature Neuroscience, 2019

30559470 (PubMed )
Supplement: NIHMS1512053-supplement-Sup_Table_5.xlsx › 5d

Genome-wide identification and analysis of A-to-I RNA editing events in the malignantly transformed cell lines from bronchial epithelial cell line induced by α-particles radiation.

Liu Q et al.

Plos One, 2019

Mammalian conserved ADAR targets comprise only a small fragment of the human editosome.

Pinto Y et al.

Genome Biology, 2014

24393560 (PubMed )
Supplement: gb-2014-15-1-r5-S1.xlsx › supplementary_table_10

Base excision repair and cancer.

Wallace SS et al.

Cancer Letters, 2012

Variation in base excision repair capacity.

Wilson DM et al.

Mutation Research, 2011

Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer.

Shinmura K et al.

Carcinogenesis, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."