Associated Papers
Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation.
Fang Z et al.
Cell Reports, 2023
Functional Interaction Between the Oncogenic Kinase NEK2 and Sam68 Promotes a Splicing Program Involved in Migration and Invasion in Triple-Negative Breast Cancer.
Naro C et al.
Frontiers in Oncology, 2022
Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma.
Deng L et al.
Journal of Experimental & Clinical Cancer Research : Cr, 2019
Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2.
Choi BK et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018
The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry.
Endicott SJ et al.
Development (cambridge, England), 2015
Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction.
Chen C et al.
Journal of Cell Science, 2015
The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.
Naro C et al.
Nucleic Acids Research, 2014
24369428 (PubMed )
Supplement: supp_gkt1307_nar-02240-a-2013-File008.pdf
Nek2 localises to the distal portion of the mother centriole/basal body and is required for timely cilium disassembly at the G2/M transition.
Spalluto C et al.
European Journal of Cell Biology, 2012
The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer.
Hayward DG et al.
Cancer Research, 2004
NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling.
Lou Y et al.
The Journal of Biological Chemistry, 2004
Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans.
Schultz SJ et al.
Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research, 1994
Cep68 can be regulated by Nek2 and SCF complex.
Man X et al.
European Journal of Cell Biology, 0
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