Varaico: Literature-Extracted Genetic Variants

Gene:NEK8
Variant:p.G442V
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NEK8

NM_178170.3:p.G442V

Associated Papers

NEK8, a NIMA-family protein kinase at the core of the ciliary INV complex.

Roig J

Cell Communication and Signaling : Ccs, 2025

ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning.

Czarnecki PG et al.

Nature Communications, 2015

NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies.

Choi HJ et al.

Molecular Cell, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."