Varaico: Literature-Extracted Genetic Variants

Gene:NES
Variant:p.K27M
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NES

NM_006617.2:p.K27M

Associated Papers

Implications of canonical histone H3.1 and histone variant H3.3 in cancer.

Wu P et al.

Open Biology, 2025

Disruption of ataxia telangiectasia-mutated kinase enhances radiation therapy efficacy in spatially directed diffuse midline glioma models.

Mangoli A et al.

The Journal of Clinical Investigation, 2025

Pediatric Hemispheric High-Grade Gliomas and H3.3-G34 Mutation: A Review of the Literature on Biological Features and New Therapeutic Strategies.

Bonada M et al.

Genes, 2024

The H3K27M mutation alters stem cell growth, epigenetic regulation, and differentiation potential.

Kfoury-Beaumont N et al.

Bmc Biology, 2022

Solid tumours hijack the histone variant network.

Ghiraldini FG et al.

Nature Reviews. Cancer, 2021

Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models.

Deland K et al.

The Journal of Clinical Investigation, 2021

Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma.

Misuraca KL et al.

Acta Neuropathologica Communications, 2014

Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications.

Buczkowicz P et al.

Acta Neuropathologica, 2014

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.

Buczkowicz P et al.

Nature Genetics, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."