Associated Papers
Genetic and Phenotypic Characterization of Nexilin (NEXN)-Related Cardiomyopathy: Results From a Multicentric Study.
Perotto M et al.
Jacc. Heart Failure, 2025
Nexilin mutations, a cause of chronic heart failure: A state-of-the-art review starting from a clinical case.
Năstasie OC et al.
World Journal of Cardiology, 2025
Nexilin in cardiomyopathy: unveiling its diverse roles with special focus on endocardial fibroelastosis.
Rahimzadeh M et al.
Heart Failure Reviews, 2024
Biallelic NEXN variants and fetal onset dilated cardiomyopathy: two independent case reports and revision of literature.
Picciolli I et al.
Italian Journal of Pediatrics, 2024
In vivo rescue of genetic dilated cardiomyopathy by systemic delivery of nexilin.
Shao Y et al.
Genome Biology, 2024
NEXN Gene in Cardiomyopathies and Sudden Cardiac Deaths: Prevalence, Phenotypic Expression, and Prognosis.
Hermida A et al.
Circulation. Genomic and Precision Medicine, 2024
Structural and signaling proteins in the Z-disk and their role in cardiomyopathies.
Noureddine M et al.
Frontiers in Physiology, 2023
Diagnostic yield of genetic testing in a multinational heterogeneous cohort of 2088 DCM patients.
Heliö K et al.
Frontiers in Cardiovascular Medicine, 2023
Determining the Likelihood of Disease Pathogenicity Among Incidentally Identified Genetic Variants in Rare Dilated Cardiomyopathy-Associated Genes.
Yang Q et al.
Journal of the American Heart Association, 2022
Loss of Nexilin function leads to a recessive lethal fetal cardiomyopathy characterized by cardiomegaly and endocardial fibroelastosis.
Johansson J et al.
American Journal of Medical Genetics. Part A, 2022
Titin M-line insertion sequence 7 is required for proper cardiac function in mice.
Biquand A et al.
Journal of Cell Science, 2021
Childhood onset nexilin dilated cardiomyopathy: A heterozygous and a homozygous case.
Bruyndonckx L et al.
American Journal of Medical Genetics. Part A, 2021
A unique case of left ventricle apical hypoplasia presenting with a type 1 Brugada ECG pattern and NEXN mutation. Are they related?
Marinelli A et al.
Heartrhythm Case Reports, 2021
Homozygous G650del nexilin variant causes cardiomyopathy in mice.
Liu C et al.
Jci Insight, 2020
Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting.
Wright CF et al.
American Journal of Human Genetics, 2019
Mutations in NEXN, a Z-disc gene, are associated with hypertrophic cardiomyopathy.
Wang H et al.
American Journal of Human Genetics, 2010
Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy.
Hassel D et al.
Nature Medicine, 2009