Associated Papers
Re-evaluation of missense variant classifications in NF2.
Sadler KV et al.
Human Mutation, 2022
35332608 (PubMed )
Supplement: HUMU-43-643-s001.xlsx › Sheet1
Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2.
Chinthalapudi K et al.
Nature Communications, 2018
Stability of the tumor suppressor merlin depends on its ability to bind paxillin LD3 and associate with β1 integrin and actin at the plasma membrane.
Manetti ME et al.
Biology Open, 2012
Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin.
Yamauchi J et al.
Experimental Cell Research, 2008
The merlin interacting proteins reveal multiple targets for NF2 therapy.
Scoles DR
Biochimica Et Biophysica Acta, 2008
Paxillin binds schwannomin and regulates its density-dependent localization and effect on cell morphology.
Fernandez-Valle C et al.
Nature Genetics, 2002
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