Associated Papers
Functional annotation of the Hippo pathway somatic mutations in human cancers.
Han H et al.
Nature Communications, 2024
39572544 (PubMed )
Supplement: 41467_2024_54480_MOESM3_ESM.zip › Supplementary_Data › Supplementary_Data_3.xlsx › All_Hippo_missense_mutations
Re-evaluation of missense variant classifications in NF2.
Sadler KV et al.
Human Mutation, 2022
35332608 (PubMed )
Supplement: HUMU-43-643-s001.xlsx › Sheet1
Prediction and evaluation of deleterious and disease causing non-synonymous SNPs (nsSNPs) in human NF2 gene responsible for neurofibromatosis type 2 (NF2).
Havranek B et al.
Journal of Biomolecular Structure & Dynamics, 2021
Phosphorylation of Merlin by Aurora A kinase appears necessary for mitotic progression.
Mandati V et al.
The Journal of Biological Chemistry, 2019
FERM domain phosphoinositide binding targets merlin to the membrane and is essential for its growth-suppressive function.
Mani T et al.
Molecular and Cellular Biology, 2011
Mutational spectrum of the NF2 gene: a meta-analysis of 12 years of research and diagnostic laboratory findings.
Ahronowitz I et al.
Human Mutation, 2007
Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor gene.
Golovnina K et al.
Bmc Evolutionary Biology, 2005
Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function.
Surace EI et al.
Oncogene, 2004
Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
Shimizu T et al.
The Journal of Biological Chemistry, 2002
The structure of the FERM domain of merlin, the neurofibromatosis type 2 gene product.
Kang BS et al.
Acta Crystallographica. Section D, Biological Crystallography, 2002
Functional analysis of neurofibromatosis 2 (NF2) missense mutations.
Gutmann DH et al.
Human Molecular Genetics, 2001
The 2.7 A crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activation.
Edwards SD et al.
Biochemistry, 2001
Loss of DAL-1, a protein 4.1-related tumor suppressor, is an important early event in the pathogenesis of meningiomas.
Gutmann DH et al.
Human Molecular Genetics, 2000
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