Varaico: Literature-Extracted Genetic Variants

Gene:NFE2
Variant:p.D122H
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NFE2

NM_001136023.3:p.D122H

Associated Papers

A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants.

Aboulkassim T et al.

Cell Reports, 2023

KEAP1 Cancer Mutants: A Large-Scale Molecular Dynamics Study of Protein Stability.

Wilson CJ et al.

International Journal of Molecular Sciences, 2021

Molecular effects of cancer-associated somatic mutations on the structural and target recognition properties of Keap1.

Khan H et al.

The Biochemical Journal, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."