Varaico: Literature-Extracted Genetic Variants

Gene:NHS
Variant:p.P301S
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NHS

NM_001291867.2:p.P301S

Associated Papers

Conformation-specific monoclonal antibodies reveal early Tau structural intermediates in Alzheimer's disease.

Tsaka G et al.

The Journal of Biological Chemistry, 2026

Seeding Alzheimer's disease-associated tau pathology in MAPT knock-in primary neurons causes early axonopathy and synaptic dysfunction.

Mueller RL et al.

Scientific Reports, 2025

Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons.

Marvian AT et al.

Molecular Neurodegeneration, 2024

DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity.

Ryder BD et al.

Structure (london, England : 1993), 2024

Motifs in the tau protein that control binding to microtubules and aggregation determine pathological effects.

Lathuilière A et al.

Scientific Reports, 2017

Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo.

Yanamandra K et al.

Neuron, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."