Varaico: Literature-Extracted Genetic Variants

Gene:NHS
Variant:p.P301L
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NHS

NM_001291867.2:p.P301L

Associated Papers

Seeding Alzheimer's disease-associated tau pathology in MAPT knock-in primary neurons causes early axonopathy and synaptic dysfunction.

Mueller RL et al.

Scientific Reports, 2025

Motifs in the tau protein that control binding to microtubules and aggregation determine pathological effects.

Lathuilière A et al.

Scientific Reports, 2017

Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments.

Levenga J et al.

Acta Neuropathologica Communications, 2013

Disease-related modifications in tau affect the interaction between Fyn and Tau.

Bhaskar K et al.

The Journal of Biological Chemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."