Varaico: Literature-Extracted Genetic Variants

Gene:NKX3-1
Variant:p.R52C
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NKX3-1

NM_006167.4:p.R52C

Associated Papers

Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.

Vanni I et al.

Journal of Translational Medicine, 2024

38750555 (PubMed )
Supplement: 12967_2024_5227_MOESM14_ESM.xlsx › S14

PhosVarDeep: deep-learning based prediction of phospho-variants using sequence information.

Liu X et al.

Peerj, 2022

Rare Tumor-Normal Matched Whole Exome Sequencing Identifies Novel Genomic Pathogenic Germline and Somatic Aberrations.

Sprissler R et al.

Cancers, 2020

32570879 (PubMed )
Supplement: cancers-12-01618-s001.zip › cancers-817200-Supplementary_Materials3 › Supplementary_table_S1.xlsx › TSG

PhosphoPICK-SNP: quantifying the effect of amino acid variants on protein phosphorylation.

Patrick R et al.

Bioinformatics (oxford, England), 2017

Variant NKX3.1 and Serum IGF-1: Investigation of Interaction in Prostate Cancer.

Muhlbradt E et al.

Genes & Cancer, 2013

Assessing high-resolution melt curve analysis for accurate detection of gene variants in complex DNA fragments.

Tindall EA et al.

Human Mutation, 2009

Genetic polymorphism and pathogenesis of benign prostatic hyperplasia.

Konwar R et al.

Bju International, 2008

Physical and functional interactions between the prostate suppressor homeoprotein NKX3.1 and serum response factor.

Ju JH et al.

Journal of Molecular Biology, 2006

Effect of homeodomain protein NKX3.1 R52C polymorphism on prostate gland size.

Rodriguez Ortner E et al.

Urology, 2006

Germ-line mutation of NKX3.1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function.

Zheng SL et al.

Cancer Research, 2006

The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression.

Wang J et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2004

[Genetic susceptibility to prostate cancer].

Cussenot O et al.

Medecine Sciences : M/s, 2004

Occurrence of NKX3.1 C154T polymorphism in men with and without prostate cancer and studies of its effect on protein function.

Gelmann EP et al.

Cancer Research, 2002

DNA-binding sequence of the human prostate-specific homeodomain protein NKX3.1.

Steadman DJ et al.

Nucleic Acids Research, 2000

Coding region of NKX3.1, a prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers.

Voeller HJ et al.

Cancer Research, 1997

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