Associated Papers
Posttranslational Regulation of Inflammasomes, Its Potential as Biomarkers and in the Identification of Novel Drugs Targets.
Nanda SK et al.
Frontiers in Cell and Developmental Biology, 2022
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.
Wang SB et al.
Science Immunology, 2021
Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface.
Moghaddas F et al.
The Journal of Allergy and Clinical Immunology, 2018
Novel aspects of the assembly and activation of inflammasomes with focus on the NLRC4 inflammasome.
Fusco WG et al.
International Immunology, 2018
LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection.
Liu W et al.
The Journal of Experimental Medicine, 2017
28821568 (PubMed )
Supplement: JEM_20170014_sm.pdf
A Disease-associated Mutant of NLRC4 Shows Enhanced Interaction with SUG1 Leading to Constitutive FADD-dependent Caspase-8 Activation and Cell Death.
Raghawan AK et al.
The Journal of Biological Chemistry, 2017
NLRP3 recruitment by NLRC4 during Salmonella infection.
Qu Y et al.
The Journal of Experimental Medicine, 2016
Phosphorylation of NLRC4 is critical for inflammasome activation.
Qu Y et al.
Nature, 2012
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