Associated Papers
Dysregulation of inflammasomes in autoinflammatory diseases.
Hou C et al.
Joint Bone Spine, 2025
Benchmarking nanopore sequencing and rapid genomics feasibility: validation at a quaternary hospital in New Zealand.
Nyaga DM et al.
Npj Genomic Medicine, 2024
Role of the NLRP1 inflammasome in skin cancer and inflammatory skin diseases.
Calabrese L et al.
The British Journal of Dermatology, 2024
Structural basis for thioredoxin-mediated suppression of NLRP1 inflammasome.
Zhang Z et al.
Nature, 2023
Current understanding of the phenotypic spectrum of patients with NLRP1 variants.
Takeichi T et al.
The British Journal of Dermatology, 2023
A homozygous p.Leu813Pro gain-of-function NLRP1 variant causes phenotypes of different severity in two siblings.
Li M et al.
The British Journal of Dermatology, 2023
Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain.
Moecking J et al.
The Journal of Biological Chemistry, 2022
Pathophysiology, clinical manifestations and current management of IL-1 mediated monogenic systemic autoinflammatory diseases, a literature review.
Li Y et al.
Pediatric Rheumatology Online Journal, 2022
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.
Harapas CR et al.
Science Immunology, 2022
NLRP1 Inflammasome Activation in Keratinocytes: Increasing Evidence of Important Roles in Inflammatory Skin Diseases and Immunity.
Fenini G et al.
The Journal of Investigative Dermatology, 2022
The NLRP1 Inflammasome Induces Pyroptosis in Human Corneal Epithelial Cells.
Griswold AR et al.
Investigative Ophthalmology & Visual Science, 2022
Molecular mechanisms of phenotypic variability in monogenic autoinflammatory diseases.
Aksentijevich I et al.
Nature Reviews. Rheumatology, 2021
NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity.
Moecking J et al.
The Journal of Allergy and Clinical Immunology, 2021
Structural and biochemical mechanisms of NLRP1 inhibition by DPP9.
Huang M et al.
Nature, 2021
The NLRP1 Inflammasome in Human Skin and Beyond.
Fenini G et al.
International Journal of Molecular Sciences, 2020
Periodic fever syndromes and the autoinflammatory diseases (AIDs).
Marino A et al.
Journal of Translational Autoimmunity, 2020
The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries.
Mitchell PS et al.
Current Opinion in Immunology, 2019
Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis.
Drutman SB et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019
Transient left bundle branch block and left ventricular dysfunction in a patient with NLRP1-associated autoinflammation with arthritis and dyskeratosis syndrome.
Garrelfs MR et al.
Cardiology in the Young, 2019
Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding.
Zhong FL et al.
The Journal of Biological Chemistry, 2018
An Update on Autoinflammatory Diseases: Inflammasomopathies.
Harapas CR et al.
Current Rheumatology Reports, 2018
A new autoinflammatory and autoimmune syndrome associated with NLRP1 mutations: NAIAD (NLRP1-associated autoinflammation with arthritis and dyskeratosis).
Grandemange S et al.
Annals of the Rheumatic Diseases, 2017
NLRP1-associated autoinflammatory disease with epithelial dyskeratosis.
Lemus-Arteaga K et al.
Pediatric Dermatology, 0