Associated Papers
ZAKα/P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome.
Rodríguez-Ruiz L et al.
Embo Molecular Medicine, 2023
Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain.
Moecking J et al.
The Journal of Biological Chemistry, 2022
Oxidized thioredoxin-1 restrains the NLRP1 inflammasome.
Ball DP et al.
Science Immunology, 2022
Autoinflammatory disease with corneal and mucosal dyskeratosis caused by a novel NLRP1 variant.
Herlin T et al.
Rheumatology (oxford, England), 2020
Autolytic proteolysis within the function to find domain (FIIND) is required for NLRP1 inflammasome activity.
Finger JN et al.
The Journal of Biological Chemistry, 2012
CARD8 and NLRP1 undergo autoproteolytic processing through a ZU5-like domain.
D'Osualdo A et al.
Plos One, 2011
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