Associated Papers
Dysregulation of inflammasomes in autoinflammatory diseases.
Hou C et al.
Joint Bone Spine, 2025
Unraveling the NLRP family: Structure, function, activation, critical influence on tumor progression, and potential as targets for cancer therapy.
Zhou X et al.
Cancer Letters, 2024
Combined therapy with IL-1 and JAK inhibitors in a patient with the NLRP1 gene mutation and a complex inflammatory phenotype.
Burlakov V et al.
The Journal of Allergy and Clinical Immunology. Global, 2024
NLRP1- A CINDERELLA STORY: a perspective of recent advances in NLRP1 and the questions they raise.
Barry K et al.
Communications Biology, 2023
A homozygous p.Leu813Pro gain-of-function NLRP1 variant causes phenotypes of different severity in two siblings.
Li M et al.
The British Journal of Dermatology, 2023
NLRP1 Inflammasome Activation in Keratinocytes: Increasing Evidence of Important Roles in Inflammatory Skin Diseases and Immunity.
Fenini G et al.
The Journal of Investigative Dermatology, 2022
The NLRP1 Inflammasome Induces Pyroptosis in Human Corneal Epithelial Cells.
Griswold AR et al.
Investigative Ophthalmology & Visual Science, 2022
The CARD8 T60 variant associates with NLRP1 and negatively regulates its activation.
Xu Z et al.
Frontiers in Immunology, 2022
Autoinflammatory disease with corneal and mucosal dyskeratosis caused by a novel NLRP1 variant.
Herlin T et al.
Rheumatology (oxford, England), 2020
The NLRP1 Inflammasome in Human Skin and Beyond.
Fenini G et al.
International Journal of Molecular Sciences, 2020
The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries.
Mitchell PS et al.
Current Opinion in Immunology, 2019
Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis.
Drutman SB et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019
An Update on Autoinflammatory Diseases: Inflammasomopathies.
Harapas CR et al.
Current Rheumatology Reports, 2018
Function and mechanism of the pyrin inflammasome.
Heilig R et al.
European Journal of Immunology, 2018
Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation.
Zhong FL et al.
Cell, 2016
NLRP1-associated autoinflammatory disease with epithelial dyskeratosis.
Lemus-Arteaga K et al.
Pediatric Dermatology, 0