Associated Papers
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants.
Feng S et al.
Nature Immunology, 2025
Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation.
Hochheiser IV et al.
Science Advances, 2022
35559676 (PubMed )
Supplement: sciadv.abn7583_data_file_s1.zip › sciadv.abn7583_data_file_s1.xlsx › Fig._3D
Computational Modeling of NLRP3 Identifies Enhanced ATP Binding and Multimerization in Cryopyrin-Associated Periodic Syndromes.
Samson JM et al.
Frontiers in Immunology, 2020
Diagnosis of cryopyrin-associated periodic syndrome: challenges, recommendations and emerging concepts.
Sarrabay G et al.
Expert Review of Clinical Immunology, 2015
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