Varaico: Literature-Extracted Genetic Variants

Gene:NLRP3
Variant:p.D303H
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NLRP3

NM_001243133.2:p.D303H

Associated Papers

Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action.

Wilhelmsen K et al.

The Journal of Experimental Medicine, 2025

Novel Insights into the Clinical Features, Genetic Spectrum and Clonal Evolution of Patients Carrying NLRP3 Mosaicism.

Bonet N et al.

Journal of Clinical Immunology, 2025

A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation.

Kim W et al.

Cell Chemical Biology, 2025

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants.

Feng S et al.

Nature Immunology, 2025

Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation.

Cosson C et al.

The Journal of Experimental Medicine, 2024

1–50 of 97 papers
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."