Associated Papers
Neonatal familial cold autoinflammatory syndrome: A newborn with recurrent cold-induced urticarial eruptions.
Nicholas T et al.
Jaad Case Reports, 2026
RM1mAb avoids Intracellular degradation to Synergistically inhibit NLRP3 Inflammasome Activation in Familial Cold Autoinflammatory Syndrome.
Lackner A et al.
Biorxiv : the Preprint Server for Biology, 2025
Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action.
Wilhelmsen K et al.
The Journal of Experimental Medicine, 2025
Dysregulation of inflammasomes in autoinflammatory diseases.
Hou C et al.
Joint Bone Spine, 2025
TH5487 specifically targets NLRP3 in FCAS patients resistant to MCC950.
Lackner A et al.
Biorxiv : the Preprint Server for Biology, 2025
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants.
Feng S et al.
Nature Immunology, 2025
Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation.
Cosson C et al.
The Journal of Experimental Medicine, 2024
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