Varaico: Literature-Extracted Genetic Variants

Gene:NLRP3
Variant:p.F523Y
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NLRP3

NM_001243133.2:p.F523Y

Associated Papers

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants.

Feng S et al.

Nature Immunology, 2025

39930093 (PubMed )
Supplement: 41590_2025_2088_MOESM3_ESM.xlsx › Table_1

Novel chemotype NLRP3 inhibitors that target the CRID3-binding pocket with high potency.

Vande Walle L et al.

Life Science Alliance, 2024

HSP90β controls NLRP3 autoactivation.

Spel L et al.

Science Advances, 2024

38416826 (PubMed )
Supplement: sciadv.adj6289_sm.pdf

Clinical characteristics of Chinese neonates with neonatal-onset multisystem inflammatory disease: a case report and literature review.

Zhao C et al.

Frontiers in Immunology, 2023

Tumor necrosis factor-alpha blockade ameliorates inflammatory response in two children with chronic infantile neurological, cutaneous and articular syndrome.

Luo XY et al.

The Journal of Dermatology, 2020

CAPS and NLRP3.

Booshehri LM et al.

Journal of Clinical Immunology, 2019

Next-generation sequencing and its initial applications for molecular diagnosis of systemic auto-inflammatory diseases.

Rusmini M et al.

Annals of the Rheumatic Diseases, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."