Associated Papers
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants.
Feng S et al.
Nature Immunology, 2025
The discovery of NLRP3 and its function in cryopyrin-associated periodic syndromes and innate immunity.
Putnam CD et al.
Immunological Reviews, 2024
Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome.
Karasawa T et al.
Elife, 2022
NLRP3 inflammasome and NLRP3-related autoinflammatory diseases: From cryopyrin function to targeted therapies.
Moltrasio C et al.
Frontiers in Immunology, 2022
Inflammasome Genetic Variants, Macrophage Function, and Clinical Outcomes in Cystic Fibrosis.
Graustein AD et al.
American Journal of Respiratory Cell and Molecular Biology, 2021
The diagnostic evaluation of patients with a suspected hereditary periodic fever syndrome: experience from a referral center in Italy.
Vitale A et al.
Internal and Emergency Medicine, 2017
Late-Onset Cryopyrin-Associated Periodic Syndromes Caused by Somatic NLRP3 Mosaicism-UK Single Center Experience.
Rowczenio DM et al.
Frontiers in Immunology, 2017
Diagnosis of cryopyrin-associated periodic syndrome: challenges, recommendations and emerging concepts.
Sarrabay G et al.
Expert Review of Clinical Immunology, 2015
Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies.
Brydges SD et al.
The Journal of Clinical Investigation, 2013
Characterization of NLRP3 variants in Japanese cryopyrin-associated periodic syndrome patients.
Ohnishi H et al.
Journal of Clinical Immunology, 2012
The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond.
Conforti-Andreoni C et al.
Cellular & Molecular Immunology, 2011
Interleukin-17 expression in the urticarial rash of familial cold autoinflammatory syndrome: a case report.
Yamauchi A et al.
The British Journal of Dermatology, 2010
Monocytes from familial cold autoinflammatory syndrome patients are activated by mild hypothermia.
Rosengren S et al.
The Journal of Allergy and Clinical Immunology, 2007
The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model.
Aksentijevich I et al.
Arthritis and Rheumatism, 2007
Response to IL-1-receptor antagonist in a child with familial cold autoinflammatory syndrome.
O'Connell SM et al.
Pediatric Dermatology, 0
Bridging the gap between the clinician and the patient with cryopyrin-associated periodic syndromes.
Cantarini L et al.
International Journal of Immunopathology and Pharmacology, 0