Associated Papers
Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action.
Wilhelmsen K et al.
The Journal of Experimental Medicine, 2025
Dysregulation of inflammasomes in autoinflammatory diseases.
Hou C et al.
Joint Bone Spine, 2025
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants.
Feng S et al.
Nature Immunology, 2025
Functional diversity of NLRP3 gain-of-function mutants associated with CAPS autoinflammation.
Cosson C et al.
The Journal of Experimental Medicine, 2024
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