Varaico: Literature-Extracted Genetic Variants

Gene:NME3
Variant:p.H135Q
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NME3

NM_002513.3:p.H135Q

Associated Papers

PRKN activation for mitophagy requires an NME3-regulated phosphatidic acid signal that separates mitochondria from endoplasmic reticulum tethering.

Chen CW et al.

Autophagy, 2026

NME3 is a gatekeeper for DRP1-dependent mitophagy in hypoxia.

Chen CW et al.

Nature Communications, 2024

Two separate functions of NME3 critical for cell survival underlie a neurodegenerative disorder.

Chen CW et al.

Proceedings of the National Academy of Sciences of the United States of America, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."