Associated Papers
Monogenic forms of inflammatory bowel disease: Genetic mechanisms, models, and clinical implications.
Ghorbanpour A et al.
Molecular Medicine (cambridge, Mass.), 2026
NOD2-Related Multisystem Inflammatory Disorders and Recent Advances.
Wu D et al.
Current Rheumatology Reports, 2026
Distinct colitis-associated macrophages drive NOD2-dependent bacterial sensing and gut homeostasis.
Katkar GD et al.
The Journal of Clinical Investigation, 2025
The emerging role of palmitoyl acyltransferase zDHHC5 in health and disease: A review.
Xiu C et al.
International Journal of Biological Macromolecules, 2025
Nucleotide-Binding Oligomerization Domain 2 in Signaling, Immunity, and Mycobacterial Infection.
Wang Y et al.
Immunity, Inflammation and Disease, 2025
Distinct Colitis-Associated Macrophages Drive NOD2-Dependent Bacterial Sensing and Gut Homeostasis.
Katkar GD et al.
Biorxiv : the Preprint Server for Biology, 2025
Genetic and immunological regulation of gut Microbiota: The Roles of TLRs, CLRs, and key proteins in microbial homeostasis and disease.
Ayoub M et al.
Gene, 2025
NOD2 Polymorphisms and Their Association with Colorectal Cancer Risk: An Updated Systematic Review and Meta-Analysis.
Sharzehan MAK et al.
Cancers, 2025
Genetic Mutations and Small Bowel Ulcerating Disease: Role in Diagnosis?
Modi R et al.
Current Gastroenterology Reports, 2025
Exploring the Relationship Between NOD2 Risk Variants and First Decompensation Events in Cirrhotic Patients With Varices.
Karbannek H et al.
Liver International : Official Journal of the International Association for the Study of the Liver, 2025
NOD2 and Crohn's Disease Clinical Practice: From Epidemiology to Diagnosis and Therapy, Rewired.
Kayali S et al.
Inflammatory Bowel Diseases, 2025
Attenuating ABHD17 isoforms augments the S-acylation and function of NOD2 and a subset of Crohn's disease-associated NOD2 variants.
Dixon CL et al.
Biorxiv : the Preprint Server for Biology, 2025
Attenuating ABHD17 Isoforms Augments the S-acylation and Function of NOD2 and a Subset of Crohn's Disease-associated NOD2 Variants.
Dixon CL et al.
Cellular and Molecular Gastroenterology and Hepatology, 2025
Goblet Cell Loss Linked to NOD2 and Secondary Resection in Crohn's Disease Is Induced by Dysbiosis and Epithelial MyD88.
Wong SY et al.
Cellular and Molecular Gastroenterology and Hepatology, 2025
Germline polymorphisms of the NOD2 pathway may predict the effectiveness of radioiodine in differentiated thyroid cancer treatment.
Borowczyk M et al.
Journal of Endocrinological Investigation, 2024
Low-Penetrance Susceptibility Variants in Colorectal Cancer-Current Outlook in the Field.
Szuman M et al.
International Journal of Molecular Sciences, 2024
The Potential Role of NOD2/CARD15 Genotype as a Prognostic Indicator for Bone Marrow Transplantation Outcomes in Patients With Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia: A Systematic Review.
Ahmadinia L et al.
Cureus, 2024
Presence of NOD2 mutations is not associated with hepatic or systemic hemodynamic abnormalities of cirrhosis.
Greinert R et al.
Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2023
Influence of NOD2 risk variants on hepatic encephalopathy and association with inflammation, bacterial translocation and immune activation.
Ripoll C et al.
Liver International : Official Journal of the International Association for the Study of the Liver, 2023
A nod to the bond between NOD2 and mycobacteria.
Dubé JY et al.
Plos Pathogens, 2023
A narrative review of precision medicine in neonatal sepsis: genetic and epigenetic factors associated with disease susceptibility.
Dai W et al.
Translational Pediatrics, 2023
Variants of NOD2 in Leishmania guyanensis-infected patients with cutaneous leishmaniasis and correlations with plasma circulating pro-inflammatory cytokines.
Mesquita TGR et al.
Plos One, 2023
Association of polymorphous light eruption with NOD-2 and TLR-5 gene polymorphisms.
Kurz B et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2022
Current perspectives on interethnic variability in multiple myeloma: Single cell technology, population pharmacogenetics and molecular signal transduction.
Gandhi M et al.
Translational Oncology, 2022
NOD2c.3019-3020insC AND c.2104C>T GENE VARIANTS AMONG PATIENTS FROM WESTERN UKRAINE WITH CROHN'S DISEASE AND COLORECTAL CANCER.
Lozynska L et al.
Experimental Oncology, 2022
Genetic associations with immune-mediated outcomes after allogeneic hematopoietic cell transplantation.
Martin PJ et al.
Blood Advances, 2022
Bladder cancer survival in patients with NOD2 or CDKN2A variants.
Złowocka-Perłowska E et al.
Oncotarget, 2022
Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function.
Mao L et al.
Frontiers in Immunology, 2022
Crohn's Disease Susceptibility and Onset Are Strongly Related to Three NOD2 Gene Haplotypes.
Kaczmarek-Ryś M et al.
Journal of Clinical Medicine, 2021
Identification and functional analysis of NOD2 and its two splicing variants associated with a novel pattern of signal regulation in teleost fishes.
Li Y et al.
Developmental and Comparative Immunology, 2021
Gene Polymorphisms of NOD2, IL23R, PTPN2 and ATG16L1 in Patients with Crohn's Disease: On the Way to Personalized Medicine?
Hoffmann P et al.
Genes, 2021
Association of rs3135500 and rs3135499 Polymorphisms in the MicroRNA-binding Site of Nucleotide-binding Oligomerization Domain 2 (NOD2) Gene with Susceptibility to Rheumatoid Arthritis.
Ehtesham N et al.
Iranian Journal of Allergy, Asthma, and Immunology, 2021
Long-Term Follow-Up, Association between CARD15/NOD2 Polymorphisms, and Clinical Disease Behavior in Crohn's Disease Surgical Patients.
Giudici F et al.
Mediators of Inflammation, 2021
Genetic Variants Assessing Crohn's Disease Pattern in Pediatric Inflammatory Bowel Disease Patients by a Clinical Exome Survey.
Noel DD et al.
Bioinformatics and Biology Insights, 2021
Missense (p.Glu778Lys) and (p.Gly908Arg) variants of NOD2 gene are associated with recurrent pulmonary non-tuberculous mycobacterial infections.
Gonzalez-Mancera MS et al.
Scandinavian Journal of Immunology, 2020
Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.
Montazeri Z et al.
Gut, 2020
Nod2 Protects the Gut From Experimental Colitis Spreading to Small Intestine.
Al Nabhani Z et al.
Journal of Crohn's & Colitis, 2020
Genetic variation in Interleukin-32 influence the immune response against New World Leishmania species and susceptibility to American Tegumentary Leishmaniasis.
Dos Santos JC et al.
Plos Neglected Tropical Diseases, 2020
The Impact of the NOD2/CARD15 Variant (3020insC) and PSMA6 Polymorphism (-8C>G) on the Development and Outcome of Multiple Myeloma.
Zmorzyński S et al.
Biomed Research International, 2020
Clinicopathological characteristics of breast cancer patients with NOD2 mutation according to age.
Huszno J et al.
Contemporary Oncology (poznan, Poland), 2020
Association between nucleotide-binding oligomerization domain protein 2 (NOD2) gene polymorphisms and Parkinson's disease (PD) susceptibility.
Xu M et al.
Artificial Cells, Nanomedicine, and Biotechnology, 2019
Rare and common variant discovery in complex disease: the IBD case study.
Venkataraman GR et al.
Human Molecular Genetics, 2019
Palmitoylation of NOD1 and NOD2 is required for bacterial sensing.
Lu Y et al.
Science (new York, N.y.), 2019
Bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation: The effect of NOD2/CARD15 mutations in a Tunisian population.
Touihri M et al.
Human Immunology, 2019
Host genetic variants in sepsis risk: a field synopsis and meta-analysis.
Lu H et al.
Critical Care (london, England), 2019
Founder Mutations for Early Onset Melanoma as Revealed by Whole Exome Sequencing Suggests That This is Not Associated with the Increasing Incidence of Melanoma in Poland.
Dębniak T et al.
Cancer Research and Treatment, 2019
Common NOD2 Risk Variants as Major Susceptibility Factors for Bacterial Infections in Compensated Cirrhosis.
Reichert MC et al.
Clinical and Translational Gastroenterology, 2019
NOD2 Expression in Intestinal Epithelial Cells Protects Toward the Development of Inflammation and Associated Carcinogenesis.
Ferrand A et al.
Cellular and Molecular Gastroenterology and Hepatology, 2019
Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease.
Nisa L et al.
Molecular Cancer Research : Mcr, 2018