Varaico: Literature-Extracted Genetic Variants

Gene:NOS3
Variant:p.S226L
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NOS3

NM_000603.5:p.S226L

Associated Papers

Evaluation of NOS3 894G>T (p.Glu298Asp) Variant as Risk Factor for Open Neural Tube Defects in Infants from Western Mexico.

Pérez-Alfaro DK et al.

Genetic Testing and Molecular Biomarkers, 2025

Leiomyoma and the importance of genetic variation on genes related to the vasculature system - CβS, MTHFR, NOS3, CYBA, and ACE1.

Inácio  et al.

European Journal of Obstetrics, Gynecology, and Reproductive Biology, 2024

Genetic variants in varicocele-related male infertility: a systematic review and future directions.

Mostafa T et al.

Human Fertility (cambridge, England), 2023

Genetics of spontaneous cervical and coronary artery dissections.

Rada I et al.

Frontiers in Global Women's Health, 2023

37214559 (PubMed )
Supplement: Table1.docx

Genetic Variants Associated with High Susceptibility of Premature Ischemic Stroke.

Isordia-Salas I et al.

Journal of the Renin-angiotensin-aldosterone System : Jraas, 2023

The Genetic Architecture of the Etiology of Lower Extremity Peripheral Artery Disease: Current Knowledge and Future Challenges in the Era of Genomic Medicine.

Butnariu LI et al.

International Journal of Molecular Sciences, 2022

Predicting drug response and toxicity in metastatic colorectal cancer: the role of germline markers.

Bignucolo A et al.

Expert Review of Clinical Pharmacology, 2022

Novel Approaches to Investigate One-Carbon Metabolism and Related B-Vitamins in Blood Pressure.

McMahon A et al.

Nutrients, 2016

Association between eNOS polymorphisms and risk of coronary artery disease in a Korean population: a meta-analysis.

Sung JH et al.

Genetics and Molecular Research : Gmr, 2015

Genetics of male infertility: from research to clinic.

Krausz C et al.

Reproduction (cambridge, England), 2015

Polymorphisms of the methylenetetrahydrofolate reductase gene (C677T and A1298C) in the placenta of pregnancies complicated with preeclampsia.

Chedraui P et al.

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology, 2015

Effect of genetic polymorphisms involved in folate metabolism on the concentration of serum folate and plasma total homocysteine (p-tHcy) in healthy subjects after short-term folic acid supplementation: a randomized, double blind, crossover study.

Cabo R et al.

Genes & Nutrition, 2015

Pharmacogenetic considerations for acute lymphoblastic leukemia therapies.

Dulucq S et al.

Expert Opinion on Drug Metabolism & Toxicology, 2014

Sickle cell disease in India.

Colah R et al.

Current Opinion in Hematology, 2014

Genetic association of rs1800780 (A→G) polymorphism of the eNOS gene with susceptibility to essential hypertension in a Chinese Han population.

Yang B et al.

Biochemical Genetics, 2014

Endothelial nitric oxide synthase gene polymorphisms and the risk of osteonecrosis of the femoral head in systemic lupus erythematosus.

Kim HS et al.

International Orthopaedics, 2013

Role of NOS3 DNA variants in externalizing behavioral problems observed in childhood leukemia survivors.

Marcoux S et al.

Journal of Pediatric Hematology/oncology, 2013

The rs1801133 polymorphism of methylenetetrahydrofolate reductase gene- the association with 5-year survival in patients with ST-elevation myocardial infarction.

Kozieradzka A et al.

Advances in Medical Sciences, 2012

Multifactor dimensionality reduction analysis of MTHFR, PAI-1, ACE, PON1, and eNOS gene polymorphisms in patients with early onset coronary artery disease.

Agirbasli M et al.

European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2011

Interaction of eNOS polymorphism with MTHFR variants increase the risk of diabetic nephropathy and its progression in type 2 diabetes mellitus patients.

Jafari Y et al.

Molecular and Cellular Biochemistry, 2011

Genetic cardiovascular risk factors and age-related macular degeneration.

Haas P et al.

Acta Ophthalmologica, 2011

Leukoaraiosis is associated with genes regulating blood-brain barrier homeostasis in ischaemic stroke patients.

Fernandez-Cadenas I et al.

European Journal of Neurology, 2011

Genes and abdominal aortic aneurysm.

Hinterseher I et al.

Annals of Vascular Surgery, 2011

First survey of the three gene polymorphisms (PON1 Q192R, eNOS E298D and eNOS C-786T) potentially associated with coronary artery spasm in African populations and comparison with worldwide data.

Fujihara J et al.

Cell Biochemistry and Function, 2011

Endothelial nitric oxide synthase haplotypes are associated with preeclampsia in Maya mestizo women.

Díaz-Olguín L et al.

Disease Markers, 2011

The Glu298ASP polymorphism of the endothelial nitric oxide synthase gene is associated with premature ST elevation myocardial infarction in Mexican population.

Isordia-Salas I et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2010

Polymorphisms of the NOS3 gene in Southern Chilean subjects with coronary artery disease and controls.

Jaramillo PC et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2010

The coagulation factor V Leiden, MTHFRC677T variant and eNOS 4ab polymorphism in young Chinese population with ischemic stroke.

Shi C et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2008

Clinical applications of bioinformatics, genomics, and pharmacogenomics.

Iqbal O et al.

Methods in Molecular Biology (clifton, N.j.), 2006

Endothelial nitric oxide synthase (NOS3) genetic variants, maternal smoking, vitamin use, and risk of human orofacial clefts.

Shaw GM et al.

American Journal of Epidemiology, 2005

Analysis of prothrombotic mutations and polymorphisms in children who developed thrombosis in the perioperative period of congenital cardiac surgery.

Ozbek N et al.

Cardiology in the Young, 2005

Endothelial nitric oxide synthase and methylenetetrahydrofolate reductase gene polymorphisms are associated with endothelial dysfunction in young, healthy men.

Imamura A et al.

The Canadian Journal of Cardiology, 2004

No association of C677T methylenetetrahydrofolate reductase and an endothelial nitric oxide synthase polymorphism with recurrent pregnancy loss.

Makino A et al.

American Journal of Reproductive Immunology (new York, N.y. : 1989), 2004

The 894 G > T variant of endothelial nitric oxide synthase (eNOS) increases the risk of recurrent venous thrombosis through interaction with elevated homocysteine levels.

Heil SG et al.

Journal of Thrombosis and Haemostasis : Jth, 2004

Pharmacogenomics for the treatment of dementia.

Cacabelos R

Annals of Medicine, 2002

Endothelial nitric oxide synthase gene polymorphism in women with idiopathic recurrent miscarriage.

Tempfer C et al.

Human Reproduction (oxford, England), 2001

C677T methylenetetrahydrofolate reductase polymorphism is not a risk factor for pre-eclampsia/eclampsia among Australian women.

Kaiser T et al.

Human Heredity, 2001

Genetics and ischaemic stroke.

Hassan A et al.

Brain : a Journal of Neurology, 2000

Endothelial nitric oxide synthase polymorphism is not associated with placental abruption in Finnish women.

Toivonen S et al.

Fetal Diagnosis and Therapy, 0

Genetic association studies of angiogenesis- and vasoconstriction-related genes in women with recurrent pregnancy loss: a systematic review and meta-analysis.

Su MT et al.

Human Reproduction Update, 0

Genetics of ischemic stroke: Indian perspective.

Kaul S et al.

Neurology India, 0

[Polimorfismos asociados a disfunción endotelial y a un estado protrombótico en jóvenes mexicanos con infarto cerebral].

Isordia-Salas I et al.

Gaceta Medica De Mexico, 0

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