Varaico: Literature-Extracted Genetic Variants

Gene:NOTCH1
Variant:p.S2467fs
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NOTCH1

NM_017617.5:p.S2467fs

Associated Papers

Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification.

Liu T et al.

Nature Communications, 2022

35347147 (PubMed )
Supplement: 41467_2022_29336_MOESM8_ESM.xlsx › Sheet1

Evaluation of the Clinical Utility of Genomic Profiling to Inform Selection of Clinical Trial Therapy in Salivary Gland Cancer.

Rack S et al.

Cancers, 2022

35267442 (PubMed )
Supplement: cancers-14-01133-s001.zip › cancers-1574535-supplementary.xlsx › Supp_Table_2_-_Variants

Molecular Profiling of Hard-to-Treat Childhood and Adolescent Cancers.

Khater F et al.

Jama Network Open, 2019

A phase I dose-escalation and dose-expansion study of brontictuzumab in subjects with selected solid tumors.

Ferrarotto R et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2018

NOTCH1 Aberrations in Chronic Lymphocytic Leukemia.

Rosati E et al.

Frontiers in Oncology, 2018

Diffuse Staining for Activated NOTCH1 Correlates With NOTCH1 Mutation Status and Is Associated With Worse Outcome in Adenoid Cystic Carcinoma.

Sajed DP et al.

The American Journal of Surgical Pathology, 2017

TIAM1 variants improve clinical outcome in neuroblastoma.

Sanmartín E et al.

Oncotarget, 2017

28423360 (PubMed )
Supplement: oncotarget-08-45286-s003.xlsx › Sheet1

Activating NOTCH1 Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Responsiveness to Notch1 Inhibitors.

Ferrarotto R et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2017

IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study.

Li Y et al.

Plos Medicine, 2016

27997540 (PubMed )
Supplement: pmed.1002200.s012.xlsx › 401_mutations

Genomic landscape of salivary gland tumors.

Kato S et al.

Oncotarget, 2015

26247885 (PubMed )
Supplement: oncotarget-06-25631-s002.xlsx › Sheet1

Hedgehog pathway mutations in T-cell acute lymphoblastic leukemia.

Dagklis A et al.

Haematologica, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."