Varaico: Literature-Extracted Genetic Variants

Gene:NOTCH1
Variant:p.V1604G
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NOTCH1

NM_017617.5:p.V1604G

Associated Papers

NOTCH1-Related Leukoencephalopathy: A Novel Variant and Literature Review.

Della Vecchia S et al.

International Journal of Molecular Sciences, 2024

PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia.

Govaerts I et al.

Journal of Hematology & Oncology, 2021

34167562 (PubMed )
Supplement: 13045_2021_1114_MOESM2_ESM.xlsx › Sheet1

Targeted sequencing to identify genetic alterations and prognostic markers in pediatric T-cell acute lymphoblastic leukemia.

Chang YH et al.

Scientific Reports, 2021

33436855 (PubMed )
Supplement: 41598_2020_80613_MOESM1_ESM.pdf

The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL.

Kampen KR et al.

Leukemia, 2019

29930300 (PubMed )
Supplement: NIHMS77878-supplement-Supplementary_information.docx

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.

Degryse S et al.

Leukemia, 2018

28852199 (PubMed )
Supplement: leu2017276x7.xlsx › Sheet1

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes.

Lindqvist CM et al.

Oncotarget, 2016

27590521 (PubMed )
Supplement: oncotarget-07-64071-s002.xlsx › Table_S4_diagnostic_mutations
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